CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035496
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Smyd1 
Protein Synonyms/Alias
 RCG56113, isoform CRA_a 
Gene Name
 Smyd1 
Gene Synonyms/Alias
 rCG_56113 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
284EHCQKGLKDDLFLAVacetylation[1]
315FSKDTLEKIDKARSEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 490 AA 
Protein Sequence
MTVGSMENVE VFTSEGKGRG LKATKEFWAA DVIFAERAYS AVVFDSLINF VCHTCFKRQE 60
RLHRCGQCKF AHYCDRTCQK DAWLNHKNEC SAIKRYGKVP NENIRLAARI MWRVEREGTG 120
LTEGCLVSVD DLQNHVEHFG EEEQKELRVD VDTFLQYWPP QSQQFSMQYI SHIFGVINCN 180
GFTLSDQRGL QAVGVGIFPN LGLVNHDCWP NCTVIFNNGN HEAVKSMFHT QMRIELRALG 240
KISEGEELTV SYIDFLHLSE ERRQQLKKQY YFDCSCEHCQ KGLKDDLFLA VKEDPKPSQE 300
VVKEMTQFSK DTLEKIDKAR SEGLYHEVVK LCRECLEKQE PVFADTNLYV LRLLSIVSEV 360
LSYLQAFEEA SHYARRMVDG YMKLYHHNNA QLGMAVMRAG LTNWHAGHIE VGHGMICKAY 420
AILLVTHGPS HPITKDLEAM RMQTEMELRM FRQNEFMYHK MREAALNNQP MQVMAEPSNE 480
PAPALFHKKQ 490 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006338; P:chromatin remodeling; IEA:Compara.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0045663; P:positive regulation of myoblast differentiation; IEA:Compara.
 GO:0010831; P:positive regulation of myotube differentiation; IEA:Compara. 
Interpro
 IPR001214; SET_dom.
 IPR002893; Znf_MYND. 
Pfam
 PF00856; SET
 PF01753; zf-MYND 
SMART
 SM00317; SET 
PROSITE
 PS50280; SET
 PS01360; ZF_MYND_1
 PS50865; ZF_MYND_2 
PRINTS