UniProt Accession

 H3BQQ2_HUMAN; H3BQQ2 

Genbank Protein ID

 AC005606 

Genbank Nucleotide ID

  

Protein Name

 Zinc finger protein 598 

Protein Synonyms/Alias

  

Gene Name

 ZNF598 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
25	RQVVFGKKLPAFATI	ubiquitination	[1]
135	HRGHPLCKFCDERYL	ubiquitination	[1]
149	LDNDELLKHLRRDHY	ubiquitination	[1, 2]
183	LREHFREKHFLCEEG	ubiquitination	[1]
208	FRTEIDLKAHRTACH	ubiquitination	[3]
282	RRGSWRYKREEEDRE	ubiquitination	[4]
795	TKSKKNKKSAWQATT	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 849 AA 

Protein Sequence

Gene Ontology

 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 

Pfam

  

SMART

 SM00355; ZnF_C2H2 

PROSITE

 PS00028; ZINC_FINGER_C2H2_1 

PRINTS