CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032231
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Potassium voltage-gated channel subfamily KQT member 2 
Protein Synonyms/Alias
 Potassium voltage-gated channel, subfamily Q, member 2 
Gene Name
 Kcnq2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
21TSGEKKLKVGFVGLDubiquitination[1]
49IAGSEAPKRGSVLSKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Potassium; Potassium channel; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 759 AA 
Protein Sequence
MVQKSRNGGV YPGTSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR GSVLSKPRTG 60
GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF LLVFSCLVLS VFSTIKEYEK 120
SSEGALYILE IVTIVVFGVE YFVRIWAAGC CCRYRGWRGR LKFARKPFCV IDIMVLIASI 180
AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL LGSVVYAHSK ELVTAWYIGF 240
LCLILASFLV YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 300
GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN LSRTDLHSTW 360
QYYERTVTVP MYRLIPPLNQ LELLRNLKSK SGLTFRKEPQ PEPSPSQKVS LKDRVFSSPR 420
GMAAKGKGSP QAQTVRRSPS ADQSLDDSPS KVPKSWSFGD RSRTRQAFRI KGAASRQNSE 480
EASLPGEDIV EDNKSCNCEF VTEDLTPGLK VSIRAVCVMR FLVSKRKFKE SLRPYDVMDV 540
IEQYSAGHLD MLSRIKSLQS RIDMIVGPPP PSTPRHKKYP TKGPTAPSRE SPQYSPRVDQ 600
IVGRGPTITD KDRTKGPAET ELPEDPSMMG RLGKVEKQVL SMEKKLDFLV SIYTQRMGIP 660
PAETEAYFGA KEPEPAPPYH SPEDSRDHAD KHGCIIKIVR STSSTGQRNY AAPPAIPPAQ 720
CPPSTSWQQS HQRHGTSPVG DHGSLVLRLE RSAGMMSCH 759 
Gene Ontology
 GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
 GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
 GO:0019226; P:transmission of nerve impulse; IMP:MGI. 
Interpro
 IPR005821; Ion_trans_dom.
 IPR003091; K_chnl.
 IPR003937; K_chnl_volt-dep_KCNQ.
 IPR003947; K_chnl_volt-dep_KCNQ2.
 IPR013821; K_chnl_volt-dep_KCNQ_C. 
Pfam
 PF00520; Ion_trans
 PF03520; KCNQ_channel 
SMART
  
PROSITE
  
PRINTS
 PR00169; KCHANNEL.
 PR01461; KCNQ2CHANNEL.
 PR01459; KCNQCHANNEL.