CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042967
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Spectrin beta chain, erythrocytic 
Protein Synonyms/Alias
  
Gene Name
 SPTB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
957KKKKHVFKLRLSNGSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1028 AA 
Protein Sequence
GKQLMDEKPQ FTALVSQKLE ALHRLWDELQ ATTKEKTQHL SAARSSDLRL QTHADLNKWI 60
SAMEDQLRSD DPGKDLTSVN RMLAKLKRVE DQVNVRKEEL GELFAQVPSM GEEGGDADLS 120
IEKRFLDLLE PLGRRKKQLE SSRAKLQISR DLEDETLWVE ERLPLAQSAD YGTNLQTVQL 180
FMKKNQTLQN EILGHTPRVE DVLQRGQQLV EAAEIDCQDL EERLGHLQSS WDRLREAAAG 240
RLQRLRDANE AQQYYLDADE AEAWIGEQEL YVISDEIPKD EEGAIVMLKR HLRQQRAVED 300
YGRNIKQLAS RAQGLLSAGH PEGEQIIRLQ GQVDKHYAGL KDVAEERKRK LENMYHLFQL 360
KRETDDLEQW ISEKELVASS PEMGQDFDHV TLLRDKFRDF ARETGAIGQE RVDNVNAFIE 420
RLIDAGHSEA ATIAEWKDGL NEMWADLLEL IDTRMQLLAA SYDLHRYFYT GAEILGLIDE 480
KHRELPEDVG LDASTAESFH RVHTAFEREL HLLGVQVQQF QDVATRLQTA YAGEKAEAIQ 540
NKEQEVSAAW QALLDACAGR RTQLVDTADK FRFFSMARDL LSWMESIIRQ IETQERPRDV 600
SSVELLMKYH QGINAEIETR SKNFSACLEL GESLLQRQHQ ASEEIREKLQ QVMSRRKEMN 660
EKWEARWERL RMLLEVCQFS RDASVAEAWL IAQEPYLASG DFGHTVDSVE KLIKRHEAFE 720
KSTASWAERF AALEKPTTLE LKERQIAERP AEETGPQEEE GETAGEAPVS HHAATERTSP 780
GEEEGTWPQN LQQPPPPGQH KDGQKSTGDE RPTTEPLFKV LDTPLSEGDE PATLPAPRDH 840
GQSVQMEGYL GRKHDLEGPN KKASNSKGEE GEERRETEEE DEEEEETESV AVEMQQHASH 900
VSWNNLYCVL RNSELTFYKD AKNLALGMPY HGEEPLALRH AICEIAANYK KKKHVFKLRL 960
SNGSEWLFHG KDEEEMLSWL QGVSTAINES QSIRVKAQSL PLPSLSGPDA SLGKKDKEKR 1020
FSFFPKKK 1028 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR018159; Spectrin/alpha-actinin.
 IPR002017; Spectrin_repeat. 
Pfam
 PF00169; PH
 PF00435; Spectrin 
SMART
 SM00233; PH
 SM00150; SPEC 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS