CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026250
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HCG20471, isoform CRA_c 
Protein Synonyms/Alias
 Sigma non-opioid intracellular receptor 1 
Gene Name
 SIGMAR1 
Gene Synonyms/Alias
 hCG_20471 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53QWREGTTKSEVFYPGubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 134 AA 
Protein Sequence
MGAMCLLHAS LSEYVLLFGT ALGSRGHSGR YWAEISDTII SGTFHQWREG TTKSEVFYPG 60
ETVVHGPGEA TAVEWGPNTW MVEYGRGVIP STLAFALADT VFSTQDFLTL FYTLRSYARG 120
LRLELTTYLF GQDP 134 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0000247; F:C-8 sterol isomerase activity; IEA:InterPro.
 GO:0004985; F:opioid receptor activity; IEA:Compara.
 GO:0006696; P:ergosterol biosynthetic process; IEA:InterPro.
 GO:0007399; P:nervous system development; IEA:Compara. 
Interpro
 IPR006716; ERG2_sigma1_rcpt-like. 
Pfam
 PF04622; ERG2_Sigma1R 
SMART
  
PROSITE
  
PRINTS