CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024499
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 RIMS-binding protein 3C 
Protein Synonyms/Alias
 RIM-BP3.C; RIMS-binding protein 3.3; RIM-BP3.3 
Gene Name
 RIMBP3C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
413CPYQADEKVKRLKVKubiquitination[1]
415YQADEKVKRLKVKRAubiquitination[1]
482QASAPLAKDKQIEELubiquitination[1]
484SAPLAKDKQIEELRQubiquitination[1]
611QLQAALLKNAWLAEEubiquitination[1]
625ENGRLQAKTDWVRKVubiquitination[1, 2]
953QMVRVGSKTEVATEIubiquitination[1]
964ATEILDTKTEACQLGubiquitination[1]
978GLLQSMGKQGLSRPLubiquitination[1]
989SRPLLGTKGVLRMAPubiquitination[1]
1217TFPVCPQKLSLAPPSubiquitination[1]
1226SLAPPSAKASPHNPGubiquitination[1]
1344RKEPCQEKAALERVLubiquitination[1]
1434LCPAPSAKVIKMPRGubiquitination[1]
1437APSAKVIKMPRGGPQubiquitination[1]
1483EEELVFQKRQLLRVWubiquitination[1]
1592GQMGGQGKGRLALRAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
 DOMAIN 832 899 SH3 1.
 DOMAIN 992 1077 Fibronectin type-III 1.
 DOMAIN 1085 1183 Fibronectin type-III 2.
 DOMAIN 1452 1520 SH3 2.
 DOMAIN 1569 1636 SH3 3.  
Keyword
 Coiled coil; Complete proteome; Reference proteome; Repeat; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1639 AA 
Protein Sequence
MAKDSPSPLG ASPKKPGCSS PAAAVLENQR RELEKLRAEL EAERAGWRAE RRRFAARERQ 60
LREEAERERR QLADRLRSKW EAQRSRELRQ LQEEMQRERE AEIRQLLRWK EAEQRQLQQL 120
LHRERDGVVR QARELQRQLA EELVNRGHCS RPGASEVSAA QCRCRLQEVL AQLRWQTDGE 180
QAARIRYLQA ALEVERQLFL KYILAHFRGH PALSGSPDPQ AVHSLEEPLP QTSSGSCHAP 240
KPACQLGSLD SLSAEVGVRS RSLGLVSSAC SSSPDGLLST HASSLDCFAP ACSRSLDSTR 300
SLPKASKSEE RPSSPDTSTP GSRRLSPPPS PLPPPPPPSA HRKLSNPRGG EGSESQPCEV 360
LTPSPPGLGH HELIKLNWLL AKALWVLARR CYTLQEENKQ LRRAGCPYQA DEKVKRLKVK 420
RAELTGLARR LADRARELQE TNLRAVSAPI PGESCAGLEL CQVFARQRAR DLSEQASAPL 480
AKDKQIEELR QECHLLQARV ASGPCSDLHT GRGGPCTQWL NVRDLDRLQR ESQREVLRLQ 540
RQLMLQQGNG GAWPEAGGQS ATCEEVRRQM LALERELDQR RRECQELGTQ AAPARRRGEE 600
AETQLQAALL KNAWLAEENG RLQAKTDWVR KVEAENSEVR GHLGRACQER DASGLIAEQL 660
LQQAARGQDR QQQLQRDPQK ALCDLHPSWK EIQALQCRPG HPPEQPWETS QMPESQVKGS 720
RRPKFHARPE DYAVSQPNRD IQEKREASLE ESPVALGESA SVPQVSETVP ASQPLSKKTS 780
SQSNSSSEGS MWATVPSSPT LDRDTASEVD DLEPDSVSLA LEMGGSAAPA APKLKIFMAQ 840
YNYNPFEGPN DHPEGELPLT AGDYIYIFGD MDEDGFYEGE LDDGRRGLVP SNFVEQIPDS 900
YIPGCLPAKS PDLGPSQLPA GQDEALEEDS LLSGKAQGMV DRGLCQMVRV GSKTEVATEI 960
LDTKTEACQL GLLQSMGKQG LSRPLLGTKG VLRMAPMQLH LQNVTATSAN ITWVYSSHRH 1020
PHVVYLDDRE HALTPAGVSC YTFQGLCPGT HYRVRVEVRL PWDLLQVYWG TMSSTVTFDT 1080
LLAGPPYPPL DVLVERHASP GVLVVSWLPV TIDSAGSSNG VQVTGYAVYA DGLKVCEVAD 1140
ATAGSTVLEF SQLQVPLTWQ KVSVRTMSLC GESLDSVPAQ IPEDFFMCHR WPETPPFSYT 1200
CGDPSTYRVT FPVCPQKLSL APPSAKASPH NPGSCGEPQA KFLEAFFEEP PRRQSPVSNL 1260
GSEGECPSSG AGSQAQELAE AWEGCRKDLL FQKSPQNHRP PSVSDQPGEK ENCYQHMGTS 1320
KSPAPGFIHL RTECGPRKEP CQEKAALERV LRQKQDAQGF TPPQLGASQQ YASDFHNVLK 1380
EEQEALCLDL RGTERREERR EPEPHSRQGQ ALGVKRGCQL HEPSSALCPA PSAKVIKMPR 1440
GGPQQLGTGA NTPARVFVAL SDYNPLVMSA NLKAAEEELV FQKRQLLRVW GSQDTHDFYL 1500
SECNRQVGNI PGRLVAEMEV GTEQTDRRWR SPAQGHLPSV AHLEDFQGLI IPQGSSLVLQ 1560
GNSKRLPLWT PKIMIAALDY DPGDGQMGGQ GKGRLALRAG DVVMVYGPMD DQGFYYGELG 1620
GHRGLVPAHL LDHMSLHGH 1639 
Gene Ontology
  
Interpro
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF07653; SH3_2 
SMART
 SM00060; FN3
 SM00326; SH3 
PROSITE
 PS50853; FN3
 PS50002; SH3 
PRINTS