UniProt Accession

 F188A_HUMAN; Q9H8M7; Q5SZ68; Q5SZ69; Q5SZ70; Q6IA40; Q6P7P0; Q7Z2S1; Q8WUF1; Q9H3I4 

Genbank Protein ID

 AB014761; AK023459; AL833873; CR457315; AF176916; AL590439; AL590439; AL590439; AL590439; CH471072; CH471072; BC020605; BC061585; BC067799; AF063600 

Genbank Nucleotide ID

 BAB87802.1; BAB14582.1; CAD38730.1; CAG33596.1; AAQ13660.1; CAI13817.1; CAI13818.1; CAI13819.1; CAI13820.1; EAW86233.1; EAW86234.1; AAH20605.1; AAH61585.1; AAH67799.1; AAG43159.1 

Protein Name

 Protein FAM188A 

Protein Synonyms/Alias

 Dermal papilla-derived protein 5; Protein CARP 

Gene Name

 FAM188A 

Gene Synonyms/Alias

 C10orf97; CARP; DERP5; MSTP126; My042 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
114	LVSWLRGKTTEETAS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May have pro-apoptotic function. Overexpression significantly inhibits cell proliferation in several tumor cell lines. 

Sequence Annotation

 MOD_RES 125 125 Phosphoserine.  

Keyword

 Alternative splicing; Apoptosis; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 445 AA 

Protein Sequence

Gene Ontology

 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 

Interpro

 IPR025257; DUF4205.
 IPR011992; EF-hand-like_dom. 

Pfam

 PF13898; DUF4205 

SMART

  

PROSITE

  

PRINTS