UniProt Accession

 CCD53_MOUSE; Q9CR27; Q8K2X5; Q9D0Y7 

Genbank Protein ID

 AK004206; AK009358; AK013835; AK158822; BC029256 

Genbank Nucleotide ID

 BAB23220.1; BAB26239.1; BAB29011.1; BAE34682.1; AAH29256.1 

Protein Name

 WASH complex subunit CCDC53 

Protein Synonyms/Alias

 Coiled-coil domain-containing protein 53 

Gene Name

 Ccdc53 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
141	PRYARYLKMVQVGVP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting (By similarity). 

Sequence Annotation

  

Keyword

 Coiled coil; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 194 AA 

Protein Sequence

Gene Ontology

 GO:0071203; C:WASH complex; ISS:UniProtKB. 

Interpro

 IPR019309; WASH_CCDC53. 

Pfam

 PF10152; DUF2360 

SMART

  

PROSITE

  

PRINTS