CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023958
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial ornithine transporter 1 
Protein Synonyms/Alias
 Solute carrier family 25 member 15 
Gene Name
 SLC25A15 
Gene Synonyms/Alias
 ORNT1; SP1855 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
145YEMETSGKIAKSQNTphosphoglycerylation[1]
245QVLSMSGKQAGFIRTubiquitination[2]
Reference
 [1] Functional lysine modification by an intrinsically reactive primary glycolytic metabolite.
 Moellering RE, Cravatt BF.
 Science. 2013 Aug 2;341(6145):549-53. [PMID: 23908237]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix. 
Sequence Annotation
 REPEAT 7 91 Solcar 1.
 REPEAT 104 197 Solcar 2.
 REPEAT 207 293 Solcar 3.  
Keyword
 Complete proteome; Disease mutation; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MKSNPAIQAA IDLTAGAAGG TACVLTGQPF DTMKVKMQTF PDLYRGLTDC CLKTYSQVGF 60
RGFYKGTSPA LIANIAENSV LFMCYGFCQQ VVRKVAGLDK QAKLSDLQNA AAGSFASAFA 120
ALVLCPTELV KCRLQTMYEM ETSGKIAKSQ NTVWSVIKSI LRKDGPLGFY HGLSSTLLRE 180
VPGYFFFFGG YELSRSFFAS GRSKDELGPV PLMLSGGVGG ICLWLAVYPV DCIKSRIQVL 240
SMSGKQAGFI RTFINVVKNE GITALYSGLK PTMIRAFPAN GALFLAYEYS RKLMMNQLEA 300
Y 301 
Gene Ontology
 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
 GO:0000064; F:L-ornithine transmembrane transporter activity; TAS:ProtInc.
 GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
 GO:0000066; P:mitochondrial ornithine transport; TAS:ProtInc.
 GO:0000050; P:urea cycle; TAS:Reactome. 
Interpro
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS