CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023676
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat and calponin homology domain-containing protein 1 
Protein Synonyms/Alias
 Calponin homology domain-containing protein 1; Neuronal protein 81; NP81 
Gene Name
 LRCH1 
Gene Synonyms/Alias
 CHDC1; KIAA1016 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
224NVRRNYLKVLPQELVubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 REPEAT 98 119 LRR 1.
 REPEAT 121 143 LRR 2.
 REPEAT 144 166 LRR 3.
 REPEAT 167 187 LRR 4.
 REPEAT 189 210 LRR 5.
 REPEAT 212 234 LRR 6.
 REPEAT 235 255 LRR 7.
 REPEAT 257 278 LRR 8.
 REPEAT 283 304 LRR 9.
 DOMAIN 576 689 CH.
 MOD_RES 568 568 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; Leucine-rich repeat; Phosphoprotein; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 728 AA 
Protein Sequence
MATPGSEPQP FVPALSVATL HPLHHPHHHH HHHQHHGGTG APGGAGGGGG GSGGFNLPLN 60
RGLERALEEA ANSGGLNLSA RKLKEFPRTA APGHDLSDTV QADLSKNRLV EVPMELCHFV 120
SLEILNLYHN CIRVIPEAIV NLQMLTYLNL SRNQLSALPA CLCGLPLKVL IASNNKLGSL 180
PEEIGQLKQL MELDVSCNEI TALPQQIGQL KSLRELNVRR NYLKVLPQEL VDLSLVKFDF 240
SCNKVLVIPI CFREMKQLQV LLLENNPLQS PPAQICTKGK VHIFKYLSIQ ACQIKTADSL 300
YLHTMERPHL HQHVEDGKKD SDSGVGSDNG DKRLSATEPS DEDTVSLNVP MSNIMEEEQI 360
IKEDSCHRLS PVKGEFHQEF QPEPSLLGDS TNSGEERDQF TDRADGLHSE FMNYKARAED 420
CEELLRIEED VHWQTEGIIS SSKDQDMDIA MIEQLREAVD LLQDPNGLST DITERSVLNL 480
YPMGSAEALE LQDSALNGQI QLETSPVCEV QSDLTLQSNG SQYSPNEIRE NSPAVSPTTN 540
STAPFGLKPR SVFLRPQRNL ESIDPQFTIR RKMEQMREEK ELVEQLRESI EMRLKVSLHE 600
DLGAALMDGV VLCHLVNHIR PRSVASIHVP SPAVPKLSMA KCRRNVENFL EACRKLGVPE 660
ADLCSPCDIL QLDFRHIRKT VDTLLALGEK APPPTSALRS RDLIGFCLVH ILFIVLVYIT 720
YHWNALSA 728 
Gene Ontology
  
Interpro
 IPR001715; CH-domain.
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp. 
Pfam
 PF00307; CH 
SMART
 SM00033; CH
 SM00369; LRR_TYP 
PROSITE
 PS50021; CH
 PS51450; LRR 
PRINTS