UniProt Accession

 TMM11_HUMAN; P17152; Q53YB2 

Genbank Protein ID

 X51804; AK311965; BT006768; AC087294; AC087393; CH471210; BC002819; BC005268; BC020815 

Genbank Nucleotide ID

 CAA36102.1; BAG34905.1; AAP35414.1; EAX02598.1; AAH02819.1; AAH05268.1; AAH20815.1 

Protein Name

 Transmembrane protein 11, mitochondrial 

Protein Synonyms/Alias

 Protein PM1; Protein PMI 

Gene Name

 TMEM11 

Gene Synonyms/Alias

 C17orf35; PM1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
142	QVEYDAYKLSRLPLH	ubiquitination	[1, 2, 3, 4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Plays a role in mitochondrial morphogenesis. 

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 192 AA 

Protein Sequence

Gene Ontology

 GO:0031305; C:integral to mitochondrial inner membrane; IDA:UniProtKB.
 GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
 GO:0007005; P:mitochondrion organization; IMP:UniProtKB. 

Interpro

 IPR026120; TMEM11. 

Pfam

  

SMART

  

PROSITE

  

PRINTS