CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043519
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RBBP6 
Protein Synonyms/Alias
  
Gene Name
 RBBP6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
768IGSNYPEKLSARDGHubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1008 AA 
Protein Sequence
MMSQSGHEYD PINYMKKPLG PPPPSYTCFR CGKPGHYIKN CPTNGDKNFE SGPRIKKSTG 60
IPRSFMMEVK DPNMKGAMLT NTGKYAIPTI DAEAYAIGKK EKPPFLPEEP SSSSEEDDPI 120
PDELLCLICK DIMTDAVVIP CCGNSYCDEC IRTALLESDE HTCPTCHQND VSPDALIANK 180
FLRQAVNNFK NETGYTKRLR KQLPPPPPPI PPPRPLIQRN LQPLMRSPIS RQQDPLMIPV 240
TSSSTHPAPS ISSLTSNQSS LAPPVSGNPS SAPAPVPDIT ATVSISVHSE KSDGPFRDSD 300
NKILPAAALA SEHSKGTSSI AITALMEEKG YQVPVLGTPS LLGQSLLHGQ LIPTTGPVRI 360
NTARPGGGRP GWEHSNKLGY LVSPPQQIRR GERSCYRSIN RGRHHSERSQ RTQGPSLPAT 420
PVFVPVPPPP LYPPPPHTLP LPPGVPPPQF SPQFPPGQPP PAGYSVPPPG FPPAPANLST 480
PWVSSGVQTA HSNTIPTTQA PPLSREEFYR EQRRLKEEEK KKSKLDEFTN DFAKELMEYK 540
KIQKERRRSF SRSKSPYSGS SYSRSSYTYS KSRSGSTRSR SYSRSFSRSH SRSYSRSPPY 600
PRRGRGKSRN YRSRSRSHGY HRSRSRSPPY RRYHSRSRSP QAFRGQSPNK RNVPQGETER 660
EYFNRYREVP PPYDMKAYYG RSVDFRDPFE KERYREWERK YREWYEKYYK GYAAGAQPRP 720
SANRENFSPE RFLPLNIRNS PFTRGRREDY VGGQSHRSRN IGSNYPEKLS ARDGHNQKDN 780
TKSKEKESEN APGDGKGNKH KKHRKRRKGE ESEGFLNPEL LETSRKSREP TGVEENKTDS 840
LFVLPSRDDA TPVRDEPMDA ESITFKSVSE KDKRERDKPK AKGDKTKRKN DGSAVSKKEN 900
IVKPAKGPQE KVDGERERSP RSEPPIKKAK EETPKTDNTK SSSSSQKDEK ITGTPRKAHS 960
KSAKEHQETK PVKEEKVKKD YSKDVKSEKL TTKEEKAKKP NEKNKPLD 1008 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001878; Znf_CCHC.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00098; zf-CCHC 
SMART
 SM00184; RING
 SM00343; ZnF_C2HC 
PROSITE
 PS50158; ZF_CCHC
 PS50089; ZF_RING_2 
PRINTS