| Tag | Content |
|---|
| CPLM ID | CPLM-017270 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | G-protein coupled receptor 56 |
Protein Synonyms/Alias | GPR56 N-terminal fragment; GPR56 NT; GPR56(N); GPR56 extracellular subunit; GPR56 subunit alpha; GPR56 C-terminal fragment; GPR56 CT; GPR56(C); GPR56 seven-transmembrane subunit; GPR56 7TM; GPR56 subunit beta |
Gene Name | Gpr56 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 674 | KNNSDSAKLPISSGS | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/Col3a1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the Col3a1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to Gna13 and possibly Gna12 (By similarity). |
Sequence Annotation | DOMAIN 343 394 GPS.
CARBOHYD 39 39 N-linked (GlcNAc...) (Potential).
CARBOHYD 148 148 N-linked (GlcNAc...) (Potential).
CARBOHYD 171 171 N-linked (GlcNAc...) (Potential).
CARBOHYD 234 234 N-linked (GlcNAc...) (Potential).
CARBOHYD 303 303 N-linked (GlcNAc...) (Potential).
CARBOHYD 324 324 N-linked (GlcNAc...) (Potential).
CARBOHYD 341 341 N-linked (GlcNAc...) (Potential). |
Keyword | Cell adhesion; Cell membrane; Complete proteome; Developmental protein; Differentiation; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Reference proteome; Secreted; Signal; Transducer; Transmembrane; Transmembrane helix; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 687 AA |
Protein Sequence | MAVQVLLQMV YFLLTLLFLV QGAHGASPRE DFRFCGQRNQ TQQSTLHYDQ TSEPHIFVWN 60
TDESLTIRAP FPAAPDIPYF FPEPRGLYHF CLYWSRHTGR LHLRYGKNDY LLSSRASNLL 120
CYRKQEESLK QGAPLVATSV SSWQSPQNTS LPGAPSFIFS FHNAPHKVSH NASVNMCDLK 180
KELQLLSKFL QHPHKASKRP SAAFISQQLQ NLESKLTSVS FLGDTLSFEE NRVNATVWKL 240
PPTAGLEDLQ IHSQQEEEQS EVQAYSVLLP RAVFQQTRGR RRDAAKRLLV VDFSSQALFQ 300
DKNSSQVLGE KVLGIVVQNT KVTNLSDPVV LTFQHQPQPK NVTLQCVFWV EDPASSSTGS 360
WSSEGCETVS RDTQTSCLCN HLTYFAVLMV SSMEVEATHK HYLTLLSYVG CVISALACVF 420
TIAAYLCTRR KSRDYTIKVH MNLLLAVFLL DVSFLLSEPV ALMGSEAACR TSAMFLHFSL 480
LACLSWMGLE GYNLYRLVVE VFGTYVPGYL LKLSTVGWGF PVFLVTLVAL VDVNNYGPII 540
LAVRRTPDHV IYPSMCWIRD SVVSYVTNLG LFSLVFLFNM AMLATMVVQI LRLRPHSQKW 600
PHVLTLLGLS LVLGLPWALV FFSFASGTFQ LVIIYLFSIM TSFQGFLIFL WYWSMRFQAQ 660
GGPSPLKNNS DSAKLPISSG STSSSRI 687 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |