CPLM-000463

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-000463

UniProt Accession

GLYG2_HUMAN; O15488; B7WNN6; O15485; O15486; O15487; O15489; O15490

Genbank Protein ID

U94362; U94363; U94364; U94357; U94358; U94360; U94361; AF179624; AF179615; AF179616; AF179617; AF179618; AF179619; AF179620; AF179621; AF179622; AF179623; AC138085; BC023152

Genbank Nucleotide ID

AAB84377.1; AAB84378.1; AAB84379.1; AAB84373.1; AAB84374.1; AAB84375.1; AAB84376.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAF61855.1; AAH23152.1

Protein Name

Glycogenin-2

Protein Synonyms/Alias

GN-2; GN2

Gene Name

GYG2

Gene Synonyms/Alias

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
486	GRIDYMGKDAFARIQ	ubiquitination	[1]

Reference

[1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]

Functional Description

Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.

Sequence Annotation

ACT_SITE 119 119 By similarity.
CARBOHYD 228 228 O-linked (Glc...).

Keyword

Alternative splicing; Complete proteome; Glycogen biosynthesis; Glycoprotein; Polymorphism; Reference proteome; Transferase.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

501 AA

Protein Sequence

MSETEFHHGA QAGLELLRSS NSPTSASQSA GMTVTDQAFV TLATNDIYCQ GALVLGQSLR 60
RHRLTRKLVV LITPQVSSLL RVILSKVFDE VIEVNLIDSA DYIHLAFLKR PELGLTLTKL 120
HCWTLTHYSK CVFLDADTLV LSNVDELFDR GEFSAAPDPG WPDCFNSGVF VFQPSLHTHK 180
LLLQHAMEHG SFDGADQGLL NSFFRNWSTT DIHKHLPFIY NLSSNTMYTY SPAFKQFGSS 240
AKVVHFLGSM KPWNYKYNPQ SGSVLEQGSA SSSQHQAAFL HLWWTVYQNN VLPLYKSVQA 300
GEARASPGHT LCHSDVGGPC ADSASGVGEP CENSTPSAGV PCANSPLGSN QPAQGLPEPT 360
QIVDETLSLP EGRRSEDMIA CPETETPAVI TCDPLSQPSP QPADFTETET ILQPANKVES 420
VSSEETFEPS QELPAEALRD PSLQDALEVD LAVSVSQISI EEKVKELSPE EERRKWEEGR 480
IDYMGKDAFA RIQEKLDRFL Q 501

Gene Ontology

GO:0005829; C:cytosol; TAS:Reactome.
GO:0008466; F:glycogenin glucosyltransferase activity; TAS:ProtInc.
GO:0006006; P:glucose metabolic process; TAS:Reactome.
GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
GO:0005980; P:glycogen catabolic process; TAS:Reactome.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.

Interpro

IPR002495; Glyco_trans_8.

Pfam

PF01501; Glyco_transf_8

SMART

PROSITE

PRINTS