CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007318
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 26A 
Protein Synonyms/Alias
 H58 protein; H beta 58; Vesicle protein sorting 26A; mVPS26 
Gene Name
 Vps26a 
Gene Synonyms/Alias
 Vps26 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
89GKVNLAFKQPGKRLEubiquitination[1]
246MELQLIKKEITGIGPubiquitination[1]
274IMDGAPVKGESIPIRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). 
Sequence Annotation
 MOD_RES 315 315 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Endosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 327 AA 
Protein Sequence
MSEPLPAFLD RLWGPWLGTR SPPSRSSAAS PSKSFLGGFF GPICEIDVAL NDGETRKMAE 60
MKTEDGKVEK HYLFYDGESV SGKVNLAFKQ PGKRLEHQGI RIEFVGQIEL FNDKSNTHEF 120
VNLVKELALP GELTQSRSYD FEFMQVEKPY ESYIGANVRL RYFLKVTIVR RLTDLVKEYD 180
LIVHQLATYP DVNNSIKMEV GIEDCLHIEF EYNKSKYHLK DVIVGKIYFL LVRIKIQHME 240
LQLIKKEITG IGPSTTTETE TIAKYEIMDG APVKGESIPI RLFLAGYDPT PTMRDVNKKF 300
SVRYFLNLVL VDEEDRRYFK QQEIILWRKA PEKLRKQRTN FHQRFESPDS QASAEQPEM 359 
Gene Ontology
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005768; C:endosome; IDA:MGI.
 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0030904; C:retromer complex; IEA:InterPro.
 GO:0031982; C:vesicle; ISS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0042147; P:retrograde transport, endosome to Golgi; IDA:MGI.
 GO:0007034; P:vacuolar transport; IEA:InterPro. 
Interpro
 IPR005377; VPS26. 
Pfam
 PF03643; Vps26 
SMART
  
PROSITE
  
PRINTS