Tag | Content |
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CPLM ID | CPLM-007318 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 26A |
Protein Synonyms/Alias | H58 protein; H beta 58; Vesicle protein sorting 26A; mVPS26 |
Gene Name | Vps26a |
Gene Synonyms/Alias | Vps26 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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89 | GKVNLAFKQPGKRLE | ubiquitination | [1] | 246 | MELQLIKKEITGIGP | ubiquitination | [1] | 274 | IMDGAPVKGESIPIR | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). |
Sequence Annotation | MOD_RES 315 315 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Endosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 327 AA |
Protein Sequence | MSEPLPAFLD RLWGPWLGTR SPPSRSSAAS PSKSFLGGFF GPICEIDVAL NDGETRKMAE 60 MKTEDGKVEK HYLFYDGESV SGKVNLAFKQ PGKRLEHQGI RIEFVGQIEL FNDKSNTHEF 120 VNLVKELALP GELTQSRSYD FEFMQVEKPY ESYIGANVRL RYFLKVTIVR RLTDLVKEYD 180 LIVHQLATYP DVNNSIKMEV GIEDCLHIEF EYNKSKYHLK DVIVGKIYFL LVRIKIQHME 240 LQLIKKEITG IGPSTTTETE TIAKYEIMDG APVKGESIPI RLFLAGYDPT PTMRDVNKKF 300 SVRYFLNLVL VDEEDRRYFK QQEIILWRKA PEKLRKQRTN FHQRFESPDS QASAEQPEM 359 |
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