CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013066
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MIF4G domain-containing protein 
Protein Synonyms/Alias
  
Gene Name
 Mif4gd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
164RVGEQLEKMNGQRMDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). 
Sequence Annotation
 DOMAIN 3 205 MIF4G.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Translation regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 222 AA 
Protein Sequence
MSEASRDDYK IQSFDAETQQ LLKTALKDPG AVDLERVANV IVDHSLQDCV FSKEAGRMCY 60
AIIQAESKQA GQSVFRRGLL NRLQKEYDAR EQLRACSLQG WVCYVTFICN IFDYLRVNNM 120
PMMALVNPVY DCLFQLAQPE SLSREEEVDC LVLQLHRVGE QLEKMNGQRM DELFILIRDG 180
FLLPTDLSSL ARLLLLEMIE FRAAGWKTTP AAHKYYYSEV SD 222 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
 GO:0016070; P:RNA metabolic process; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR016021; MIF4-like_typ_1/2/3.
 IPR003890; MIF4G-like_typ-3. 
Pfam
 PF02854; MIF4G 
SMART
  
PROSITE
  
PRINTS