CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041931
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Carboxylesterase 3B 
Protein Synonyms/Alias
 MCG133953, isoform CRA_a 
Gene Name
 Ces3b 
Gene Synonyms/Alias
 mCG_133953 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
361KSLNILDKLEHLSREubiquitination[1]
452PSSFAKFKPAWVKADacetylation[2]
457KFKPAWVKADHASENacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 571 AA 
Protein Sequence
MTNMRTMIPA GSSVLVWVTC LLLAFVTTVT GPKVIQPEVD TPLGRVRGRQ VGVKDTDRMV 60
NVFLGIPFAQ APVGPLRFSA PLPPQPWEGV RDASINPPMC LQDVEKMINS RFGLNEKIKI 120
FPISEDCLTL NIYSPTEITA GDKRPVMVWI HGGSLLVGSS TSQDGSALAA YGDVVVVTVQ 180
YRLGIFGFLS TGDKHMPGNR GFLDVVAALR WVQGNIAPFG GDPNCVTIFG NSAGGMIVSS 240
LFLSPISAGL FHRAISQSGI VTTIMMEDMK PWPEAQNFAN SVACGSASPA ELVQCLLQKE 300
GKDLIKQKNV NISYIVNDSF FPQRPEKLLA DQQFPTVPYL LGVTNHEFGW LLLKSLNILD 360
KLEHLSREDL LEISRPFLAI MEVPPEIMPT VIDEYLDNGS DQSATRYAFQ ELLGDISFII 420
PTLNFSKYLR DAGCPVFLYE FQHTPSSFAK FKPAWVKADH ASENSFVFGG PFLTDESSLL 480
AFPEATEEEK QLSLTMMAQW SQFARTGNPN GKGLPPWPQL NQLEQYLEIG LESRTGVKLK 540
KGRLQFWTET LPRKIQEWHR EQRSRKVPEE L 571 
Gene Ontology
 GO:0004091; F:carboxylesterase activity; IBA:RefGenome. 
Interpro
 IPR002018; CarbesteraseB.
 IPR019826; Carboxylesterase_B_AS.
 IPR019819; Carboxylesterase_B_CS. 
Pfam
 PF00135; COesterase 
SMART
  
PROSITE
 PS00122; CARBOXYLESTERASE_B_1
 PS00941; CARBOXYLESTERASE_B_2 
PRINTS