CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016618
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tripartite motif-containing protein 14 
Protein Synonyms/Alias
 PU.1-binding protein 
Gene Name
 Trim14 
Gene Synonyms/Alias
 Kiaa0129; Pub 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
68EEAVRVQKLIQDCLEubiquitination[1]
106KVYADSSKAWLTQKFubiquitination[1]
128DEEEVLAKKFIDKSTubiquitination[1]
133LAKKFIDKSTQLTLQubiquitination[1]
151EQAETCGKQIEVMDDubiquitination[1]
230TPMDTRLKENINCQLubiquitination[1]
244LSNSSSTKPGALLKTubiquitination[1]
250TKPGALLKTSPSPERubiquitination[1]
262PERALFLKYARTPTLubiquitination[1]
363NRESWCVKRYDLEYWubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Inhibits the transcriptional activity of SPI1 in a dose- dependent manner. 
Sequence Annotation
 DOMAIN 247 440 B30.2/SPRY.
 ZN_FING 17 59 B box-type.
 MOD_RES 105 105 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MASETTEARA PFQPDGAYGW RCPEHSERPA ELFCRRCGRC VCALCPVLGA HRGHPVGLAE 60
EEAVRVQKLI QDCLECLATK KRQHADNIAH LEDAGERLKV YADSSKAWLT QKFTELRLLL 120
DEEEVLAKKF IDKSTQLTLQ VYREQAETCG KQIEVMDDFS TRVWGIGQEP NPVQLLQAYI 180
ATKTEMGQQM SPSELSHPVP LSFEPVKNFF KEFVEAIGNT LQTPMDTRLK ENINCQLSNS 240
SSTKPGALLK TSPSPERALF LKYARTPTLD PDTMHARLRL SPDGLTVRCS LLGRLGPRPA 300
PRFDALRQVL GRDGFAAGRH YWEVDVQEAG VGWWVGAAYP SLRRRGASAA ARLGCNRESW 360
CVKRYDLEYW AFHDGQRSRL RPRRDPHRLG VFLDYEAGIL AFYDVAGGMS HLHTFHAAFQ 420
EPLYPALRLW EGPISIPRLP 440 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt.
 IPR000315; Znf_B-box. 
Pfam
 PF00622; SPRY
 PF00643; zf-B_box 
SMART
 SM00336; BBOX
 SM00589; PRY
 SM00449; SPRY 
PROSITE
 PS50188; B302_SPRY
 PS50119; ZF_BBOX 
PRINTS
 PR01407; BUTYPHLNCDUF.