| Tag | Content |
|---|
| CPLM ID | CPLM-024441 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Amyloid protein-binding protein 2 |
Protein Synonyms/Alias | Amyloid beta precursor protein-binding protein 2; APP-BP2 |
Gene Name | Appbp2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 198 | TYMDKLSKHGQQANR | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (By similarity). |
Sequence Annotation | REPEAT 50 83 TPR 1.
REPEAT 120 153 TPR 2.
REPEAT 206 239 TPR 3.
REPEAT 288 321 TPR 4.
REPEAT 333 367 TPR 5.
REPEAT 429 462 TPR 6.
REPEAT 471 505 TPR 7.
REPEAT 514 547 TPR 8. |
Keyword | Complete proteome; Cytoplasm; Cytoskeleton; Membrane; Microtubule; Nucleus; Protein transport; Reference proteome; Repeat; TPR repeat; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 585 AA |
Protein Sequence | MAAVELEWIP ETLYNTAISA VVDNYIRSRR DIRSLPENIQ FDVYYKLYQQ GRLCQLGSEF 60
CELEVFAKVL RALDKRHLLH HCFQALMDHG VKVASVLAYS FSRRCSYIAE SDAAVKEKAI 120
QVGFVLGGFL SDAGWYSDAE KVFLSCLQLC TLHDEMLHWF RAVECCVRLL HVRNGNCKYH 180
LGEETFKLAQ TYMDKLSKHG QQANRAALYG ELCALLFAKS HYDEAYKWCV EAMKEITSGL 240
PVKVVVDVLR QASKACVVKR EFKKAEQLIK HAVYLARDHF GSKHPKYSDT LLDYGFYLLN 300
VDNICQSVAI YQAALDIRQS VFGGKNIHVA TAHEDLAYSS YVHQYSSGKF DNALFHAERA 360
IGIITHILPE DHLLLASSKR VKALILEEIA IDCHNKETEQ RLLQEAHDLH LSSLQLAKKA 420
FGEFNVQTAK HYGNLGRLYQ SMRKFKEAEE MHIKAIQIKE QLLGQEDYEV ALSVGHLASL 480
YNYDMNQYEN AEKLYLRSIA IGKKLFGEGY SGLEYDYRGL IKLYNSTGNY EKVFEYHNVL 540
SNWNRLRDRQ YSVTDALEDV NSSPQSTEEV VQSFLMSQNV EGPSC 585 |
Gene Ontology | GO:0030659; C:cytoplasmic vesicle membrane; IEA:Compara. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0046907; P:intracellular transport; IEA:Compara. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |