CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027335
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein 70 (HSP70) homologue 
Protein Synonyms/Alias
  
Gene Name
 PFI0875w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
323SETLTRAKFEELNDDacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 652 AA 
Protein Sequence
MKQIRPYILL LIVSLLKFIS AVDSNIEGPV IGIDLGTTYS CVGVFKNGRV EILNNELGNR 60
ITPSYVSFVD GERKVGEAAK LEATLHPTQT VFDVKRLIGR KFDDQEVVKD RSLLPYEIVN 120
NQGKPNIKVQ IKDKDTTFAP EQISAMVLEK MKEIAQSFLG KPVKNAVVTV PAYFNDAQRQ 180
ATKDAGTIAG LNIVRIINEP TAAALAYGLD KKEETSILVY DLGGGTFDVS ILVIDNGVFE 240
VYATAGNTHL GGEDFDQRVM DYFIKMFKKK NNIDLRTDKR AIQKLRKEVE IAKRNLSVVH 300
STQIEIEDIV EGHNFSETLT RAKFEELNDD LFRETLEPVK KVLDDAKYEK SKIDEIVLVG 360
GSTRIPKIQQ IIKEFFNGKE PNRGINPDEA VAYGAAIQAG IILGEELQDV VLLDVTPLTL 420
GIETVGGIMT QLIKRNTVIP TKKSQTFSTY QDNQPAVLIQ VFEGERALTK DNHLLGKFEL 480
SGIPPAQRGV PKIEVTFTVD KNGILHVEAE DKGTGKSRGI TITNDKGRLS KEQIEKMIND 540
AEKFADEDKN LREKVEAKNN LDNYIQSMKA TVEDKDKLAD KIEKEDKNTI LSAVKDAEDW 600
LNNNSNADSE ALKQKLKDLE AVCQPIIVKL YGQPGGPSPQ PSGDEDVDSD EL 652 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.