CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037456
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microtubule-associated protein 
Protein Synonyms/Alias
  
Gene Name
 MAP4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
461TQPTSLPKQPAPTTIubiquitination[1]
668NTSAPDLKNVRSKVGubiquitination[1]
681VGSTENIKHQPGGGRubiquitination[1]
805FKEKAQAKVGSLDNVubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Microtubule; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 887 AA 
Protein Sequence
METTGDQGIE GMAYMDENRN ITFTCPRTPS ELINKSSPLE VLESAACEKL PTPTPQVVKE 60
GDSFPDTLAK NGQEIAPAQI SKSLMVDNYT KDGVPGQERP KGPSAVVPST STGGVALPIT 120
TAIETVNIHG DHSLKNKAEL ADSMKNEAGI DEGHVIGESE SVHSGASKHS VEKVTELAKG 180
HLLPGVPVED QSLPGEARAL EGYADRGNFP AHPVNEEKET KEGSVAVQIP DLLEDKAQKL 240
SFCEDQNAQD RNSKGSDSLN KKVDLTLLSP KSENDKLKEI SLACKITELE SVSLPTPEIQ 300
SDFLHSKVEA PPSEVADTLV IMTASKGVRL PEPKDKILET PQKMTEKSES KTPGEGKKED 360
KSRMAEPMKG YMRPTKSRGL TPLLPKSTIQ EQERHKQLKS AGIARPEEGR PVVSGTGNDI 420
TTPPNKELPP SPEKKTKPLA TTQPAKTSTS KAKTQPTSLP KQPAPTTIGG LNKKPMSLAS 480
GLVPAAPPKR PAVASARPSI LPSKDVKPKP IADAKAPEKR ASPSKPASAP ASRSGSKSTQ 540
TVAKTTTAAA VASTGPSSRS PSTLLPKKPT AIKTEGKPAE VKKMTAKSVP ADLSRPKSTS 600
TSSMKKTTTL SGTAPAAGVV PSRVKATPMP SRPSTTPFID KKPTSAKPSS TTPRLSRLAT 660
NTSAPDLKNV RSKVGSTENI KHQPGGGRAK VEKKTEAAAT TRKPESNAVT KTAGPIASAQ 720
KQPAGKVQIV SKKVSYSHIQ SKCGSKDNIK HVPGGGNVQI QNKKVDISKV SSKCGSKANI 780
KHKPGGGDVK IESQKLNFKE KAQAKVGSLD NVGHLPAGGA VKTEGGGSEA PLCPGPPAGE 840
EPAISEAAPE AGAPTSASGL NGHPTLSGGG DQREAQTLDS QIQETSI 887 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW. 
Interpro
 IPR027324; MAP2/MAP4/Tau.
 IPR027323; MAP4.
 IPR001084; Tau/MAP_tubulin-bd_rpt. 
Pfam
 PF00418; Tubulin-binding 
SMART
  
PROSITE
 PS00229; TAU_MAP_1
 PS51491; TAU_MAP_2 
PRINTS