CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043063
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Signal recognition particle 14 kDa protein 
Protein Synonyms/Alias
  
Gene Name
 SRP14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19ELTRLFQKCRTSGSVubiquitination[1]
43RTKPIPKKGTVEGFEubiquitination[1, 2, 3]
55GFEPADNKCLLRATDubiquitination[1]
66RATDGKKKISTVVSSubiquitination[3]
74ISTVVSSKEVNKFQMubiquitination[1, 2, 3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 115 AA 
Protein Sequence
MVLLESEQFL TELTRLFQKC RTSGSVYITL KKYDGRTKPI PKKGTVEGFE PADNKCLLRA 60
TDGKKKISTV VSSKEVNKFQ MVSFGCSLCF PSQGKSQYDS EHWVRLILGF TALRR 115 
Gene Ontology
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:InterPro.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro. 
Interpro
 IPR003210; Signal_recog_particle_SRP14.
 IPR009018; Signal_recog_particle_SRP9/14. 
Pfam
 PF02290; SRP14 
SMART
  
PROSITE
  
PRINTS