UniProt Accession

 ERP29_HUMAN; P30040; C9J183; Q3MJC3; Q6FHT4 

Genbank Protein ID

 X94910; AA412124; CR541667; AC073575; BC101493; BC101495 

Genbank Nucleotide ID

 CAA64397.1; CAG46468.1; AAI01494.1; AAI01496.1 

Protein Name

 Endoplasmic reticulum resident protein 29 

Protein Synonyms/Alias

 ERp29; Endoplasmic reticulum resident protein 28; ERp28; Endoplasmic reticulum resident protein 31; ERp31 

Gene Name

 ERP29 

Gene Synonyms/Alias

 C12orf8; ERP28 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	LDTVTFYKVIPKSKF	ubiquitination	[1, 2, 3]
137	VPYTGAVKVGAIQRW	ubiquitination	[2]
182	EARQALLKQGQDNLS	ubiquitination	[1, 2, 3]
243	GKKEELQKSLNILTA	ubiquitination	[1, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. 

Sequence Annotation

 MOTIF 258 261 Prevents secretion from ER (By  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 261 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IDA:MGI.
 GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.
 GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.
 GO:0006886; P:intracellular protein transport; TAS:ProtInc.
 GO:0009306; P:protein secretion; IEA:InterPro. 

Interpro

 IPR016855; ER_p29.
 IPR011679; ER_p29_C.
 IPR012883; ERp29_N.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF07749; ERp29
 PF07912; ERp29_N 

SMART

  

PROSITE

 PS00014; ER_TARGET 

PRINTS