UniProt Accession

 ATPO_YEAST; P09457; D6VSS7 

Genbank Protein ID

 X12356; M32487; U28374; AY557732; BK006938 

Genbank Nucleotide ID

 CAA30917.1; AAA34836.1; AAB64734.1; AAS56058.1; DAA12137.1 

Protein Name

 ATP synthase subunit 5, mitochondrial 

Protein Synonyms/Alias

 ATP synthase chain 5; Oligomycin sensitivity conferral protein; OSCP 

Gene Name

 ATP5 

Gene Synonyms/Alias

 OSCP; YDR298C; D9740.11 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
59	AAFQSLQKVESTVKK	acetylation	[1]
149	SAEPLDPKSFKRIEK	acetylation	[1]
156	KSFKRIEKALSASKL	acetylation	[1]
171	VGQGKSLKLENVVKP	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. 

Sequence Annotation

  

Keyword

 ATP synthesis; Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 212 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0000274; C:mitochondrial proton-transporting ATP synthase, stator stalk; IMP:SGD.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IDA:SGD. 

Interpro

 IPR000711; ATPase_F1-cplx_OSCP/dsu.
 IPR020781; ATPase_F1-cplx_OSCP/dsu_CS.
 IPR026015; ATPase_OSCP/delta_N. 

Pfam

 PF00213; OSCP 

SMART

  

PROSITE

 PS00389; ATPASE_DELTA 

PRINTS

 PR00125; ATPASEDELTA.