CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032491
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aldehyde dehydrogenase 9 family, member A1 
Protein Synonyms/Alias
  
Gene Name
 ALDH9A1 
Gene Synonyms/Alias
 hCG_21745 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54ADASGTEKAFEPATGubiquitination[1]
92AFKIWSQKSGMERCRubiquitination[2]
327VQKEILDKFTEEVVKubiquitination[1, 2]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 518 AA 
Protein Sequence
MFLRAGLAAL SPLLRSLRPS PVAAMSTGTF VVSQPLNYRG GARVEPADAS GTEKAFEPAT 60
GRVIATFTCS GEKEVNLAVQ NAKAAFKIWS QKSGMERCRI LLEAARIIRE REDEIATMEC 120
INNGKSIFEA RLDIDISWQC LEYYAGLAAS MAGEHIQLPG GSFGYTRREP LGVCVGIGAW 180
NYPFQIASWK SAPALACGNA MVFKPSPFTP VSALLLAEIY SEAGVPPGLF NVVQGGAATG 240
QFLCQHPDVA KVSFTGSVPT GMKIMEMSAK GIKPVTLELG GKSPLIIFSD CDMNNAVKGA 300
LMANFLTQGQ VCCNGTRVFV QKEILDKFTE EVVKQTQRIK IGDPLLEDTR MGPLINRPHL 360
ERVLGFVKVA KEQGAKVLCG GDIYVPEDPK LKDGYYMRPC VLTNCRDDMT CVKEEIFGPV 420
MSILSFDTEA EVLERANDTT FGLAAGVFTR DIQRAHRVVA ELQAGTCFIN NYNVSPVELP 480
FGGYKKSGFG RENGRVTIEY YSQLKTVCVE MGDVESAF 518 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:Compara.
 GO:0009437; P:carnitine metabolic process; IEA:Compara. 
Interpro
 IPR016161; Ald_DH/histidinol_DH.
 IPR016163; Ald_DH_C.
 IPR016160; Ald_DH_CS.
 IPR016162; Ald_DH_N.
 IPR015590; Aldehyde_DH_dom. 
Pfam
 PF00171; Aldedh 
SMART
  
PROSITE
 PS00070; ALDEHYDE_DEHYDR_CYS
 PS00687; ALDEHYDE_DEHYDR_GLU 
PRINTS