CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005544
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vegetative catalase 
Protein Synonyms/Alias
  
Gene Name
 katA 
Gene Synonyms/Alias
 kat; kat-19; BSU08820 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
39QDVHLLEKLAHFNREacetylation[1]
72EVTNDVTKYTKAAFLacetylation[1]
222FKTEQGVKNLDVNTAacetylation[1]
285VTKVWSQKDYPLIEVacetylation[1]
445ENIVNAMKPVEKEEIacetylation[1]
469KADPEYGKRVAEGLGacetylation[1]
480EGLGLPIKKDS****acetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
 Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. 
Sequence Annotation
 ACT_SITE 54 54 By similarity.
 ACT_SITE 127 127 By similarity.
 METAL 337 337 Iron (heme axial ligand) (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 483 AA 
Protein Sequence
MSSNKLTTSW GAPVGDNQNS MTAGSRGPTL IQDVHLLEKL AHFNRERVPE RVVHAKGAGA 60
HGYFEVTNDV TKYTKAAFLS EVGKRTPLFI RFSTVAGELG SADTVRDPRG FAVKFYTEEG 120
NYDIVGNNTP VFFIRDAIKF PDFIHTQKRD PKTHLKNPTA VWDFWSLSPE SLHQVTILMS 180
DRGIPATLRH MHGFGSHTFK WTNAEGEGVW IKYHFKTEQG VKNLDVNTAA KIAGENPDYH 240
TEDLFNAIEN GDYPAWKLYV QIMPLEDANT YRFDPFDVTK VWSQKDYPLI EVGRMVLDRN 300
PENYFAEVEQ ATFSPGTLVP GIDVSPDKML QGRLFAYHDA HRYRVGANHQ ALPINRARNK 360
VNNYQRDGQM RFDDNGGGSV YYEPNSFGGP KESPEDKQAA YPVQGIADSV SYDHYDHYTQ 420
AGDLYRLMSE DERTRLVENI VNAMKPVEKE EIKLRQIEHF YKADPEYGKR VAEGLGLPIK 480
KDS 483 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004096; F:catalase activity; IEA:EC.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR018028; Catalase.
 IPR020835; Catalase-like_dom.
 IPR024708; Catalase_AS.
 IPR024711; Catalase_clade1/3.
 IPR011614; Catalase_core.
 IPR002226; Catalase_haem_BS.
 IPR010582; Catalase_immune_responsive. 
Pfam
 PF00199; Catalase
 PF06628; Catalase-rel 
SMART
 SM01060; Catalase 
PROSITE
 PS00437; CATALASE_1
 PS00438; CATALASE_2
 PS51402; CATALASE_3 
PRINTS
 PR00067; CATALASE.