CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026920
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0617 protein 
Protein Synonyms/Alias
  
Gene Name
 Cul3 
Gene Synonyms/Alias
 mKIAA0617 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
259NSASVYIKKVEARINubiquitination[1]
286STEEPIVKVVERELIubiquitination[1]
316VHMLKNGKTEDLACMubiquitination[1]
373IQGLLDLKSRFDRFLubiquitination[1]
692VNDQFTSKLHRVKIQubiquitination[1]
766LPSPVVIKKRIEGLIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 792 AA 
Protein Sequence
HRRLRVRAAA AAAVSAAAGE GPSTMSNLSK GTGSRKDTKM RIRAFPMTMD EKYVNSIWDL 60
LKNAIQEIQR KNNSGLSFEE LYRNAYTMVL HKHGEKLYTG LREVVTEHLI NKVREDVLNS 120
LNNNFLQTLN QAWNDHQTAM VMIRDILMYM DRVYVQQNNV ENVYNLGLII FRDQVVRYGC 180
IRDHLRQTLL DMIARERKGE VVDRGAIRNA CQMLMILGLE GRSVYEEDFE APFLEMSAEF 240
FQMESQKFLA ENSASVYIKK VEARINEEIE RVMHCLDKST EEPIVKVVER ELISKHMKTI 300
VEMENSGLVH MLKNGKTEDL ACMYKLFSRV PNGLKTMCEC MSCYLREQGK ALVSEEGEGK 360
NPVDYIQGLL DLKSRFDRFL QESFNNDRLF KQTIAGDFEY FLNLNSRSPE YLSLFIDDKL 420
KKGVKGLTEQ EVETILDKAM VLFRFMQEKD VFERYYKQHL ARRLLTNKSV SDDSEKNMIS 480
KLKTECGCQF TSKLEGMFRD MSISNTTMDE FRQHLQATGV SLGGVDLTVR VLTTGYWPTQ 540
SATPKCNIPP APRHAFEIFR RFYLAKHSGR QLTLQHHMGS ADLNATFYGP VKKEDGSEVG 600
VGGAQVTGSN TRKHILQVST FQMTILMLFN NREKYTFEEI QQETDIPERE LVRALQSLAC 660
GKPTQRVLTK EPKSKEIESG HIFTVNDQFT SKLHRVKIQT VAAKQGESDP ERKETRQKVD 720
DDRKHEIEAA IVRIMKSRKK MQHNVLVAEV TQQLKARFLP SPVVIKKRIE GLIEREYLAR 780
TPEDRKVYTY VA 792 
Gene Ontology
 GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Compara.
 GO:0005827; C:polar microtubule; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0016477; P:cell migration; IEA:Compara.
 GO:0048208; P:COPII vesicle coating; IEA:Compara.
 GO:0008054; P:cyclin catabolic process; IEA:Compara.
 GO:0000910; P:cytokinesis; IEA:Compara.
 GO:0035024; P:negative regulation of Rho protein signal transduction; IEA:Compara.
 GO:0006513; P:protein monoubiquitination; IEA:Compara.
 GO:0043149; P:stress fiber assembly; IEA:Compara. 
Interpro
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin
 PF10557; Cullin_Nedd8 
SMART
 SM00182; CULLIN
 SM00884; Cullin_Nedd8 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2 
PRINTS