Tag | Content |
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CPLM ID | CPLM-019142 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | EP300-interacting inhibitor of differentiation 2B |
Protein Synonyms/Alias | EID-2B; EID-2-like inhibitor of differentiation 3; EID-3 |
Gene Name | EID2B |
Gene Synonyms/Alias | EID3 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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126 | RLFVEGCKAREAAFD | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Acts as a repressor of MYOD-dependent transcription, glucocorticoid receptor-dependent transcription, and muscle differentiation. |
Sequence Annotation | |
Keyword | Complete proteome; Developmental protein; Differentiation; Myogenesis; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 161 AA |
Protein Sequence | MAEPTGLLEM SELPGDSSVP QVGTASGVSD VLRGAVGGGV RVQEAREGPV AEAARSMARM 60 PGPVPGPIPS SVPGLASAPD PHQQLAFLEI NRQLLFREYL DGSSMIPVRL LRDFEERRRL 120 FVEGCKAREA AFDADPPQMD FAAVAFTVAL TASEALSPLA D 161 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007517; P:muscle organ development; IEA:UniProtKB-KW. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |