CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028938
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Pabpc4 
Protein Synonyms/Alias
  
Gene Name
 Pabpc4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
78TMNFDVMKGKPIRIMubiquitination[1]
95QRDPSLRKSGVGNVFubiquitination[1]
108VFIKNLDKSIDNKALacetylation[2, 3, 4]
108VFIKNLDKSIDNKALubiquitination[1]
157AADKAIEKMNGMLLNubiquitination[1]
186REAELGAKAKEFTNVubiquitination[1]
188AELGAKAKEFTNVYIubiquitination[1]
216ELFSQFGKTLSVKVMubiquitination[1]
284KRKFEQLKQERISRYubiquitination[1]
361NGRIVGSKPLYVALAacetylation[3]
361NGRIVGSKPLYVALAsuccinylation[3]
361NGRIVGSKPLYVALAubiquitination[1]
375AQRKEERKAHLTNQYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 631 AA 
Protein Sequence
MNAAASSYPM ASLYVGDLHS DVTEAMLYEK FSPAGPVLSI RVCRDMITRR SLGYAYVNFQ 60
QPADAERALD TMNFDVMKGK PIRIMWSQRD PSLRKSGVGN VFIKNLDKSI DNKALYDTFS 120
AFGNILSCKV VCDENGSKGY AFVHFETQEA ADKAIEKMNG MLLNDRKVFV GRFKSRKERE 180
AELGAKAKEF TNVYIKNFGE EVDDGNLKEL FSQFGKTLSV KVMRDSSGKS KGFGFVSYEK 240
HEDANKAVEE MNGKEMSGKA IFVGRAQKKV ERQAELKRKF EQLKQERISR YQGVNLYIKN 300
LDDTIDDEKL RREFSPFGSI TSAKVMLEDG RSKGFGFVCF SSPEEATKAV TEMNGRIVGS 360
KPLYVALAQR KEERKAHLTN QYMQRVAGMR ALPASAILNQ FQPAAGGYFV PAVPQAQGRP 420
PYYTPNQLAQ MRPNPRWQQG GRPQGFQGMP SALRQSGPRP ALRHLAPTGN APASRGLPTT 480
AQRVGVPTAV PNLAPRAAVA AAAPRAVAPY KYASSVRSPH PAIQPLQAPQ PAVHVQGQEP 540
LTASMLAAAP PQEQKQMLGE RLFPLIQTMH SNLAGKITGM LLEIDNSELL HMLESPESLR 600
SKVDEAVAVL QAHHAKKEAA QKVGTVAAAT S 631 
Gene Ontology
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR006515; PABP_1234.
 IPR002004; PABP_HYD.
 IPR000504; RRM_dom. 
Pfam
 PF00658; PABP
 PF00076; RRM_1 
SMART
 SM00517; PolyA
 SM00360; RRM 
PROSITE
 PS51309; PABC
 PS50102; RRM 
PRINTS