UniProt Accession

 SDPR_MOUSE; Q63918; Q3V1P6; Q78EC3; Q8CBT4 

Genbank Protein ID

 S67386; AK035324; AK084096; AK132324; BC020008; BC027005 

Genbank Nucleotide ID

 AAB28953.1; BAC29033.1; BAC39116.1; BAE21104.1; AAH20008.1; AAH27005.1 

Protein Name

 Serum deprivation-response protein 

Protein Synonyms/Alias

 Cavin-2; Phosphatidylserine-binding protein 

Gene Name

 Sdpr 

Gene Synonyms/Alias

 Sdr 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
91	INLEGSVKGIQNDLT	ubiquitination	[1]
99	GIQNDLTKLSKYQAS	ubiquitination	[1]
102	NDLTKLSKYQASTSN	acetylation	[2]
102	NDLTKLSKYQASTSN	ubiquitination	[1]
113	STSNTVSKLLEKSRK	acetylation	[3]
113	STSNTVSKLLEKSRK	ubiquitination	[1]
173	IPASVFVKEPVPSAA	ubiquitination	[1]
183	VPSAAEGKEELADEN	ubiquitination	[1]
261	KMNKLGTKIVSVERR	ubiquitination	[1]
291	SGKSSPFKVSPLSFG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 May play a role in targeting PRKCA to caveolae (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylglycine (By similarity).
 MOD_RES 203 203 Phosphoserine.
 MOD_RES 204 204 Phosphoserine.
 MOD_RES 218 218 Phosphoserine.
 MOD_RES 288 288 Phosphoserine.
 MOD_RES 293 293 Phosphoserine.
 MOD_RES 359 359 Phosphoserine.
 MOD_RES 363 363 Phosphoserine.
 MOD_RES 368 368 Phosphothreonine.  

Keyword

 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Lipid-binding; Membrane; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 418 AA 

Protein Sequence

Gene Ontology

 GO:0005901; C:caveola; IEA:UniProtKB-SubCell.
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISO:MGI. 

Interpro

 IPR026752; Cavin_fam. 

Pfam

  

SMART

  

PROSITE

  

PRINTS