UniProt Accession

 CD48_HUMAN; P09326; Q5U055 

Genbank Protein ID

 M59904; X06341; M37766; BT019813; AL121985; CH471121; BC016182; M63911 

Genbank Nucleotide ID

 AAA62834.1; CAA29647.1; AAA36211.1; AAV38616.1; CAC00578.1; EAW52705.1; AAH16182.1; AAA35602.1 

Protein Name

 CD48 antigen 

Protein Synonyms/Alias

 B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48 

Gene Name

 CD48 

Gene Synonyms/Alias

 BCM1; BLAST1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
124	NEQEWKIKLQVLDPV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. 

Sequence Annotation

 DOMAIN 29 127 Ig-like C2-type 1.
 DOMAIN 132 212 Ig-like C2-type 2.
 LIPID 220 220 GPI-anchor amidated serine.
 CARBOHYD 40 40 N-linked (GlcNAc...) (Potential).
 CARBOHYD 44 44 N-linked (GlcNAc...) (Potential).
 CARBOHYD 104 104 N-linked (GlcNAc...).
 CARBOHYD 162 162 N-linked (GlcNAc...) (Potential).
 CARBOHYD 178 178 N-linked (GlcNAc...); atypical.
 CARBOHYD 189 189 N-linked (GlcNAc...).
 DISULFID 154 196 Potential.  

Keyword

 3D-structure; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; GPI-anchor; Immunoglobulin domain; Lipoprotein; Membrane; Polymorphism; Reference proteome; Repeat; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 243 AA 

Protein Sequence

Gene Ontology

 GO:0046658; C:anchored to plasma membrane; IEA:Compara.
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0045121; C:membrane raft; IDA:UniProtKB.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0003823; F:antigen binding; IEA:Compara.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0007596; P:blood coagulation; TAS:Reactome.
 GO:0006952; P:defense response; TAS:ProtInc.
 GO:0050900; P:leukocyte migration; TAS:Reactome.
 GO:0045576; P:mast cell activation; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:Compara.
 GO:0042110; P:T cell activation; IEA:Compara. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set.
 IPR015631; SLAM_fam_rcpts. 

Pfam

 PF07686; V-set 

SMART

 SM00409; IG 

PROSITE

 PS50835; IG_LIKE 

PRINTS