| Tag | Content |
|---|
| CPLM ID | CPLM-017203 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptide chain release factor 1, mitochondrial |
Protein Synonyms/Alias | MRF-1; MtRF-1 |
Gene Name | Mtrf1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 143 | SLCKSLNKQDEKQLQ | acetylation | [1] |
|
Reference | [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice. Simon GM, Cheng J, Gordon JI. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [ PMID: 22733758] |
Functional Description | Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA (By similarity). |
Sequence Annotation | MOD_RES 314 314 N5-methylglutamine (By similarity). |
Keyword | Complete proteome; Methylation; Mitochondrion; Protein biosynthesis; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 446 AA |
Protein Sequence | MSHHLCIWLF RNPFLRACPQ RHVFLSCQQF RQISLDTRPW NFRQKKTHVL YQLLNKSWSR 60
GCCHQGTRKL WKHKALQKYM EDLNKEYQTL DQCLQGISEN EGDRRALHRR HAQLAPLAAV 120
YQEIQEAEQA IEELESLCKS LNKQDEKQLQ ELVSEERQII DQKIHRLYSE LLERLVPKEK 180
YDWSDVILEV TSGRTTGGDI CQQFTREIFD MYQNYSYYKH WKFELLNYTP ADYGGLHHAA 240
ARISGDSVYK HLKYEGGIHR VQRIPEVGLS SRMQRIHTGT MSVIVLPQPD EVDVKVDPKD 300
LRVDTFRARG AGGQHVNTTD SAVRLVHIPT GLVVECQQER SQLKNKEIAL RVLRARLYQQ 360
IIEKDRCQQQ NARKLQVGTR AQSERIRTYN FTQDRVTDHR IAYEVRDIKE FLRGEKCLDQ 420
LIERLLQSAD EEAISEFLDE SLQSVK 446 |
Gene Ontology | GO:0005739; C:mitochondrion; IDA:MGI. GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |