CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020686
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial 
Protein Synonyms/Alias
 Integral membrane protein CII-3; QPs-1; QPs1 
Gene Name
 Sdhc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
35APLGTTAKEEMERFWacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753
Functional Description
 Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). 
Sequence Annotation
 METAL 127 127 Iron (heme axial ligand); shared with  
Keyword
 Complete proteome; Electron transport; Heme; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
MAAFLLRHVS RHCLRAHLNA QLCIRNAAPL GTTAKEEMER FWKKNTSSNR PLSPHLTIYK 60
WSLPMALSVC HRGSGIALSG GVSLFGLSAL LLPGNFESYL MFVKSLCLGP TLIYSAKFVL 120
VFPLMYHSLN GIRHLLWDLG KGLAIPQVWL SGVAVVVLAV LSSGGLAAL 169 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005749; C:mitochondrial respiratory chain complex II; ISS:UniProtKB.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; ISS:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0000104; F:succinate dehydrogenase activity; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway. 
Interpro
 IPR018495; Succ_DH_cyt_bsu_CS.
 IPR014314; Succ_DH_cytb556.
 IPR014361; Succ_DH_cytb560.
 IPR000701; Succ_DH_Fumarate_Rdtase_TM-su. 
Pfam
 PF01127; Sdh_cyt 
SMART
  
PROSITE
 PS01000; SDH_CYT_1
 PS01001; SDH_CYT_2 
PRINTS