CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG10638, isoform B 
Protein Synonyms/Alias
 IP08705p 
Gene Name
 CG10638-RB 
Gene Synonyms/Alias
 CG10638; Dmel_CG10638 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
63IIGKVLAKLIGDQKLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 ACT_SITE 51 51 Proton donor (By similarity).  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 310 AA 
Protein Sequence
MKLAPTVKLN NGYEMPILGL GTYNLKKSRC EAAVCHALEM GYRHIDTAYL YRNEGIIGKV 60
LAKLIGDQKL KREQVFLVTK LWDIYHEPKM VKYACDMQLK LLGVDYIDLY LMHSPVGVDY 120
ISDEDLMPHE NGQLRTNDVD YVDTYRSMEQ LVHLGLVRSL GLSNFNANQL KRLLENCQIK 180
PANLQIECHP ELVQVPLIEL CKFHNITVVA YSPLGRPKAC NPLPDYYTDS KLLALAAKYG 240
KTPAQIILRY LIDIGTVPIP KAAQRAHLVE NLDIFDFHLT PEELLQMKTF NTGRRIWKFD 300
KAKNHQYYPY 310 
Gene Ontology
 GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2 
PRINTS
 PR00069; ALDKETRDTASE.