CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039318
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Enolase 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
247SEFYRAGKYDLDFKSacetylation[1]
272DQLADLYKSFIKDYPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 REGION 358 361 Substrate binding (By similarity).
 ACT_SITE 201 201 Proton donor (By similarity).
 ACT_SITE 331 331 Proton acceptor (By similarity).
 BINDING 150 150 Substrate (By similarity).
 BINDING 159 159 Substrate (By similarity).
 BINDING 284 284 Substrate (By similarity).
 BINDING 306 306 Substrate (By similarity).
 BINDING 382 382 Substrate (By similarity).  
Keyword
 Complete proteome; Glycolysis; Lyase; Magnesium; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 421 AA 
Protein Sequence
RTLPCSFSRE IFDSRGNPTI EVDLYTAKGL FRVPSSASTG IYDTLALRDD DKTCFMGKGV 60
SKAVEHINNT MAPALVSKKE KIDQLMMEMD GTENKSKSGA NAFLGVSLAV CKAGAVEKGV 120
SLYRHIIDLA GNPEVILPVP AFNVINGVSH AGNKLAMQEF MILPVGASSF QEAMCTGADV 180
YHNLKNVLKE KNGDDTNVGD EGGFAPNNLE NKEALELLKS AMAKAGYTDQ VVIGMDVAAS 240
EFYRAGKYDL DFKSPDDASR YITPDQLADL YKSFIKDYPV VSIEDSFDWD AWQKFTATAG 300
IQVVGDDLTM ANPKRIAKAA GQKSCNCFLP KVNQIGSVTE SLQACKLAQS NGWGVMVSHR 360
SGENEDTFIA DLVVGICTGQ IKTGDPCLSE RLAKYNQILS IEEELGSKAR FAGRSFRNPL 420
A 421 
Gene Ontology
 GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004634; F:phosphopyruvate hydratase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 
Interpro
 IPR000941; Enolase.
 IPR020810; Enolase_C.
 IPR020811; Enolase_N. 
Pfam
 PF00113; Enolase_C
 PF03952; Enolase_N 
SMART
  
PROSITE
  
PRINTS
 PR00148; ENOLASE.