UniProt Accession

 PAQR3_HUMAN; Q6TCH7; A8K5B7; B3KP59; Q6PIQ1; Q86X05; Q8NCP9 

Genbank Protein ID

 AY424281; AK055774; AK291232; BC029604; BC031256; BC047510 

Genbank Nucleotide ID

 AAR08369.1; BAG51571.1; BAF83921.1; AAH31256.1; AAH47510.1 

Protein Name

 Progestin and adipoQ receptor family member 3 

Protein Synonyms/Alias

 Progestin and adipoQ receptor family member III; Raf kinase trapping to Golgi; RKTG 

Gene Name

 PAQR3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
4	****MHQKLLKSAHY	ubiquitination	[1]
41	EQIPGSLKDNPYITD	ubiquitination	[1, 2]
302	VMQYRHSKPCPDYVS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi. 

Sequence Annotation

 REGION 61 71 Golgi targeting.
 REGION 299 303 Golgi targeting.  

Keyword

 Alternative splicing; Complete proteome; Golgi apparatus; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 311 AA 

Protein Sequence

Gene Ontology

 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR004254; HlyIII-related. 

Pfam

 PF03006; HlyIII 

SMART

  

PROSITE

  

PRINTS