UniProt Accession

 ATX1_YEAST; P38636; D6W0T4; E9P8W0 

Genbank Protein ID

 L35270; X96722; Z71535; AY558367; BK006947 

Genbank Nucleotide ID

 AAC37428.1; CAA65485.1; CAA96166.1; AAS56693.1; DAA10300.1 

Protein Name

 Metal homeostasis factor ATX1 

Protein Synonyms/Alias

  

Gene Name

 ATX1 

Gene Synonyms/Alias

 YNL259C; N0840 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
28	AVNKVLTKLEPDVSK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Shuttles copper to the transport ATPase CCC2. Protects against oxygen toxicity. 

Sequence Annotation

 DOMAIN 5 69 HMA.
 METAL 15 15 Copper.
 METAL 18 18 Copper.  

Keyword

 3D-structure; Chaperone; Complete proteome; Copper; Copper transport; Cytoplasm; Ion transport; Metal-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 73 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:SGD.
 GO:0016531; F:copper chaperone activity; IDA:SGD.
 GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
 GO:0006825; P:copper ion transport; IMP:SGD. 

Interpro

 IPR017969; Heavy-metal-associated_CS.
 IPR006121; HeavyMe-assoc_HMA. 

Pfam

 PF00403; HMA 

SMART

  

PROSITE

 PS01047; HMA_1
 PS50846; HMA_2 

PRINTS