CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032521
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasome subunit alpha type 
Protein Synonyms/Alias
  
Gene Name
 TGGT1_012060, TGVEG_076410 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
117FIAQVQQKYTHRGGVacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protease; Proteasome; Reference proteome; Threonine protease. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 245 AA 
Protein Sequence
MSYDRAITVF SPDGHLLQVE YAMEAVRRGG CAVGVMGKDL VVLAVEKKAA ARLQEPRTAR 60
KVVMLDENLC LAFAGLHADA RVLINKTRVE CQSYRLNTAT APSVDYISKF IAQVQQKYTH 120
RGGVRPFGLS CLIAGAEHDG SIALYQTEPS GICAKWKAQA MGKNYRTVQE YLEKNYAPDL 180
DEDGAVHLAV GALMEVVEAG HRHIEVAVVK KEQFYFLDED RLEKEAQRVE SLKNSEEESK 240
SSGSS 245 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
 GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR000426; Proteasome_asu_N.
 IPR023332; Proteasome_suA-type.
 IPR001353; Proteasome_sua/b. 
Pfam
 PF00227; Proteasome
 PF10584; Proteasome_A_N 
SMART
 SM00948; Proteasome_A_N 
PROSITE
 PS00388; PROTEASOME_A_1
 PS51475; PROTEASOME_A_2 
PRINTS