CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020471
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L15, mitochondrial 
Protein Synonyms/Alias
 L15mt; MRP-L15 
Gene Name
 Mrpl15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
248YVLPDITKDELFRMLacetylation[1]
291PTDENLLKYYSS***acetylation[2, 3]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [3] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MAGTARGCGT SLDLLRSLPR VSLANLKPSP NSRKRERRPR DRRRGRKCGR GHKGERQRGT 60
RPRLGFEGGQ TPFYIRIPKY GFNEGHSFRH QYQPLSLRRL QYLIDLGRVD PTQPIDLTQL 120
VNGRGVTIQP LKRDYGVQLV EEGADTFQAK INIEVQLASE LAIAAIEKNG GVVTTAFYDP 180
RSLEILCKPI PFFLRGQPIP KRMLPPESLV PYYTDAKNRG YLADPAKFPE ARLELAMKFG 240
YVLPDITKDE LFRMLSARKD PRQIFFGLAP GWVVNMADKK ILKPTDENLL KYYSS 295 
Gene Ontology
 GO:0005762; C:mitochondrial large ribosomal subunit; ISA:MGI.
 GO:0003735; F:structural constituent of ribosome; ISA:MGI.
 GO:0000002; P:mitochondrial genome maintenance; TAS:MGI.
 GO:0006412; P:translation; ISA:MGI. 
Interpro
 IPR005749; Ribosomal_L15_bac-type.
 IPR021131; Ribosomal_L18e/L15P. 
Pfam
 PF00828; Ribosomal_L18e 
SMART
  
PROSITE
 PS00475; RIBOSOMAL_L15 
PRINTS