| Tag | Content |
|---|
| CPLM ID | CPLM-018477 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Stromal membrane-associated protein 1 |
Protein Synonyms/Alias | |
Gene Name | Smap1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 31 | LLREEDNKYCADCEA | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis. |
Sequence Annotation | DOMAIN 18 143 Arf-GAP.
ZN_FING 33 56 C4-type.
MOTIF 192 196 Interaction with clathrin heavy chains. |
Keyword | Cell membrane; Complete proteome; GTPase activation; Membrane; Metal-binding; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 440 AA |
Protein Sequence | MATRSCREKA QKLNEQHQLI LSKLLREEDN KYCADCEAKG PRWASWNIGV FICIRCAGIH 60
RNLGVHISRV KSVNLDQWTP EQIQCMQDMG NTKARLLYEA NLPENFRRPQ TDQAVEFFIR 120
DKYEKKKYYD KNAIAITNKE KEKKKDEKKR EKEPEKPAKP LTTEKLPKKE EQQLEPKKST 180
SPKNAAEPTI DLLGLDGPAE APVTNGNPAT APALSDDLDI FGPMISNPLP AAVMPPAQGT 240
ASVPAPATLS TVTSGDLDLF TEQTTKSEEV AKKQLSKDSI LSLYGTGAQQ STPGVFMGPT 300
NIPFTSQAPT AFQGFPSMGV PVPAAPGLIG NMMGQNTGMM VGMPMHNGFM GNAQTGVMPL 360
PQNVVGPQGG MVGQMGAPQS KFGLPQAQQP QWNLSQMNQQ MAAMNLSSAN ASAGFGQPPS 420
TTAGWSGSSS GQTLSTQLWK 440 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:MGI. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0008060; F:ARF GTPase activator activity; IDA:MGI. GO:0030276; F:clathrin binding; IDA:MGI. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI. GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |