UniProt Accession

 RAS1_YEAST; P01119; D6W2G2 

Genbank Protein ID

 K01970; X00527; X94335; Z75009; U32307; BK006948 

Genbank Nucleotide ID

 AAA34958.1; CAA25206.1; CAA64023.1; CAA99298.1; AAC49087.1; DAA10878.1 

Protein Name

 Ras-like protein 1 

Protein Synonyms/Alias

  

Gene Name

 RAS1 

Gene Synonyms/Alias

 YOR101W; YOR3205W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
5	***MQGNKSTIREYK	ubiquitination	[1]
49	TIEDSYRKQVVIDDK	ubiquitination	[1]
143	EDGLRLAKQLNAPFL	ubiquitination	[1]
177	LVRDDGGKYNSMNRQ	ubiquitination	[1]
207	ATADREKKNNGSYVL	ubiquitination	[1]
244	TTKRTDEKNYVNQNN	ubiquitination	[1]
258	NNNEGNTKYSSNGNG	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 The S.cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP. 

Sequence Annotation

 NP_BIND 17 24 GTP (By similarity).
 NP_BIND 64 68 GTP (By similarity).
 NP_BIND 123 126 GTP (By similarity).
 MOTIF 39 47 Effector region (By similarity).
 MOD_RES 306 306 Cysteine methyl ester.
 LIPID 305 305 S-palmitoyl cysteine.
 LIPID 306 306 S-farnesyl cysteine.  

Keyword

 Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Palmitate; Prenylation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 309 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IMP:SGD.
 GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:SGD.
 GO:0007265; P:Ras protein signal transduction; TAS:SGD.
 GO:0001302; P:replicative cell aging; IMP:SGD. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR020849; Small_GTPase_Ras. 

Pfam

 PF00071; Ras 

SMART

 SM00173; RAS 

PROSITE

 PS51421; RAS 

PRINTS

 PR00449; RASTRNSFRMNG.