CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myh14 
Protein Synonyms/Alias
  
Gene Name
 Myh14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
710NHEKRAGKLEPRLVLacetylation[1]
861QWWRLFIKVKPLLQVacetylation[1]
994RQKLQLEKVTTEAKMacetylation[1]
1042QAAEEEEKVKSLNKLacetylation[1]
1052SLNKLRVKYEATIADacetylation[1]
1076KGRQELEKLKRRLDGacetylation[1]
1323ALSEAESKAIRLSKEacetylation[1]
1469QLLSTLEKKQRKFDQacetylation[1]
1482DQLLAEEKAAVLRAVacetylation[1]
1583LTAAEDAKLRLEVTVacetylation[1]
1642LAMAARKKLELELEEacetylation[1]
1661TSAAGQGKEEAVKQLacetylation[1]
1676KKMQAQMKELWREVEacetylation[1]
1803AERSFSAKAESGRQQacetylation[1]
1863RERILSGKLVRRAEKacetylation[1]
1895QLRDQLEKSNLRLKQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2000 AA 
Protein Sequence
MATVTLSVPG RKVASRPGPV PEAAQPFLFA PRTPNVGGPG GPQVEWTARR MVWVPSELHG 60
FEAAALRDEG EEEAEVELAE SGRRLRLPRD QIQRMNPPKF SKAEDMAELT CLNEASVLHN 120
LRERYYSGLI YTYSGLFCVV INPYKQLPIY TEAIVEMYRG KKRHEVPPHI YAVTEGAYRS 180
MLQDREDQSI LCTGESGAGK TENTKKVIQY LAHVASSPKG RKEPGVPASV STMSYGELER 240
QLLQANPILE AFGNAKTVKN DNSSRFGKFI RINFDIAGYI VGANIETYLL EKSRAIRQAK 300
DECSFHIFYQ LLGGAGEQLK ADLLLEPYSH YRFLTNGPSS SPGQERELFQ ETLESLRVLG 360
LLPEEITAML RTVSAVLQFG NIVLKKERNT DQATMPDNTA AQKLCRLLGL GVTDFSRALL 420
TPRIKVGRDY VQKAQTKEQA DFALEALAKA TYERLFRWLV LRLNRALDRS PRQGASFLGI 480
LDIAGFEIFQ LNSFEQLCIN YTNEKLQQLF NHTMFVLEQE EYQREGIPWT FLDFGLDLQP 540
CIDLIERPAN PPGLLALLDE ECWFPKATDK SFVEKVAQEQ GSHPKFQRPR NLRDQADFSV 600
LHYAGKVDYK ANEWLMKNMD PLNDNVAALL HQSTDRLTAE IWKDVEGIVG LEQVSSLGDG 660
PPGGRPRRGM FRTVGQLYKE SLSRLMATLS NTNPSFVRCI VPNHEKRAGK LEPRLVLDQL 720
RCNGVLEGIR ICRQGFPNRI LFQEFRQRYE ILTPNAIPKG FMDGKQACEK MIQALELDPN 780
LYRVGQSKIF FRAGVLAQLE EERDLKVTDI IVSFQAAARG YLARRAFQRR QQQQSALRVM 840
QRNCAAYLKL RNWQWWRLFI KVKPLLQVTR QDEVLQARAQ ELQKVQELQQ QSAREVGELQ 900
GRVAQLEEER ARLAEQLRAE AELCSEAEET RARLAARKQE LELVVTELEA RVGEEEECSR 960
QLQSEKKRLQ QHIQELETHL EAEEGARQKL QLEKVTTEAK MKKFEEDLLL LEDQNSKLSK 1020
ERRLLEERLA EFSSQAAEEE EKVKSLNKLR VKYEATIADM EDRLKKEEKG RQELEKLKRR 1080
LDGESSELQE QMMEQKQRAE ELLIQLGRKE EELQSALVRA EEEGGARAQL LKSLREAQAG 1140
LAEAQEDLEA ERVARAKAEK QRRDLGEELE ALRGELEDTL DSTNAQQELR SKREQEVTEL 1200
KKTLEEEART HEVAMQELRQ RHSQALVELT EQLEQARRGK SVWEKTRLSL EAEVSELKTE 1260
LSSLQTSRQE GEQKRRRLES QLQEVQGRSS DSERARAEAA EKLQRAQVEL ESVSTALSEA 1320
ESKAIRLSKE LSSAESQLHD TQELLQEETR AKLALGSRVR ALEAEAAGLR EQMEEEVVAR 1380
ERAGRELQTT QAQLSEWRRR QEEEAAVLEA GEEARRRAAR EAETLAQRLA EKTEAVERLE 1440
RARRRLQQEL DDATVDLGQQ KQLLSTLEKK QRKFDQLLAE EKAAVLRAVE DRERVEAEGR 1500
EREARALSLT RALEEEQEAR EELERQNRAL RAELEALLSS KDDVGKNVHE LERARRVAEQ 1560
AASDLRTQVT ELEDELTAAE DAKLRLEVTV QALKAQHERD LQGRDDAGEE RRRQLAKQLR 1620
DAEVERDEER KQRALAMAAR KKLELELEEL KAQTSAAGQG KEEAVKQLKK MQAQMKELWR 1680
EVEETRSSRE EMFTLSRESE KRLKGLEAEV LRLQEELAAS DRARRQAQQD RDEMAEEVAS 1740
GNLSKAATLE EKRQLEGRLG QLEEELEEEQ NNSELLKDHY RKLVLQVETL TTELSAERSF 1800
SAKAESGRQQ LERQIQELRA RLGEEDAGAR ARQKMLIAAL ESKLAQAEEQ LEQESRERIL 1860
SGKLVRRAEK RLKEVVLQVD EERRVADQLR DQLEKSNLRL KQLKRQLEEA EEEASRAQAG 1920
RRRLQRELED VTESAESMNR EVTTLRNRLR RGPLTFTTRT VRQVFRLEEG VASDEEEAEG 1980
AEPGSAPTQE PEAPPPAAPQ 2000 
Gene Ontology
 GO:0030424; C:axon; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0001725; C:stress fiber; IEA:Compara.
 GO:0030898; F:actin-dependent ATPase activity; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0000146; F:microfilament motor activity; IEA:Compara.
 GO:0030048; P:actin filament-based movement; IEA:Compara. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.