CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Rab GTPase-binding effector protein 1 
Protein Synonyms/Alias
 Rabaptin, RAB GTPase binding effector protein 1, isoform CRA_a 
Gene Name
 Rabep1 
Gene Synonyms/Alias
 rCG_33950 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
107QEAIDEVKRQWREEVubiquitination[1]
282QLKHTWQKANDQFLEacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 862 AA 
Protein Sequence
MAQPGPAPQP DVSLQQRVAE LEKINAEFLR AQQQLEQEFN QKRAKFKELY LAKEEDLKRQ 60
NAVLQAAQDD LGHLRTQLWE AQAEMENIKA IATVSENTKQ EAIDEVKRQW REEVASLQAV 120
MKETVRDYEH QFHLRLEQER AQWAQYRESA DREIADLRRR LSEGQEEENL ENEMKKAQED 180
AEKLRSVVMP MEKEIAALKD KLTEAEDKIK ELEASKVKEL NHYLEAEKSC RTDLEMYVAV 240
LNTQKSVLQE DAEKLRKELH EVCHLLEQER QQHNQLKHTW QKANDQFLES QRLLMRDMQR 300
MEIVLTSEQL RQVEELKKKD QEEDEQQRIN KGKDNKKIDT EEEVKIPVVC ALTQEESSTP 360
LSNEEEHLDS THGSVHSLDA DLLLPSGDPF SKSDNDMFKE GLRRAQSTDS LGTSSSLQSK 420
ALGYNYKAKS AGNLDESDFG PLVGADSVSE NFDTVSLGSL QMPSGFMLTK DQERAIKAMT 480
PEQEETASLL SSVTQGMESA YVSPSGYLLV SETEWNLLQK EVHNAGNKLG RRCDMCSNYE 540
KQLQGIQIQE AETRDQVKKL QLMLRQANDQ LEKTMKEKQE LEDFLRQSAE DSSHQISALV 600
LRAQASEVLL EELQQSFSQA KRDVQEQMAV LMQSREQVSE ELVRLQKDND SLQGKHSLHV 660
SLQLAEDFIL PDTVQVLREL VLKYRENIVH VRTAADHMEE KLKAEILFLK EQIQAEQCLK 720
ENLEETLQLE IENCKEEIAS ISSLKAELER IKVEKGQLES TLREKSQQLE SLQEIKVNLE 780
EQLKKETAAK ATVEQLMFEE KNKAQRLQTE LDVSEQVQRD FVKLSQTLQV QLERIRQADS 840
LERIRAILND TKLTDINQLP ET 862 
Gene Ontology
 GO:0030139; C:endocytic vesicle; IEA:Compara.
 GO:0005768; C:endosome; IEA:Compara.
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. 
Interpro
 IPR003914; Rabaptin.
 IPR018514; Rabaptin_coiled-coil.
 IPR015390; Rabaptin_Rab5-bd_dom. 
Pfam
 PF09311; Rab5-bind
 PF03528; Rabaptin 
SMART
  
PROSITE
  
PRINTS
 PR01432; RABAPTIN.