CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032211
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ethanolamine-phosphate cytidylyltransferase 
Protein Synonyms/Alias
 cDNA, FLJ79284, highly similar to Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) 
Gene Name
 PCYT2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34DEEIAKHKGPPVFTQubiquitination[1]
46FTQEERYKMVQAIKWubiquitination[2]
98RDTYEEVKQAGRYREubiquitination[1, 2]
147EYADSFGKCPGGRNPubiquitination[2, 3]
334RNQKKEAKELAFLEAubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleotidyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 357 AA 
Protein Sequence
MVHYGHSNQL RQARAMGDYL IVGVHTDEEI AKHKGPPVFT QEERYKMVQA IKWVDEVVPA 60
APYVTTLETL DKYNCDFCVH GNDITLTVDG RDTYEEVKQA GRYRECKRTQ GVSTTDLVGR 120
MLLVTKAHHS SQEMSSEYRE YADSFGKCPG GRNPWTGVSQ FLQTSQKIIQ FASGKEPQPG 180
ETVIYVAGAF DLFHIGHVDF LEKVHRLAER PYIIAGLHFD QEVNHYKGKN YPIMNLHERT 240
LSVLACRYVS EVVIGAPYAV TAELLSHFKV DLVCHGKTEI IPDRDGSDPY QEPKRRGIFR 300
QIDSGSNLTT DLIVQRIITN RLEYEARNQK KEAKELAFLE AARQQAAQPL GERDGDF 357 
Gene Ontology
 GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
 GO:0009058; P:biosynthetic process; IEA:InterPro. 
Interpro
 IPR004821; Cyt_trans-like.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF01467; CTP_transf_2 
SMART
  
PROSITE
  
PRINTS