CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035168
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutaryl-Coenzyme A dehydrogenase (Predicted) 
Protein Synonyms/Alias
 Protein Gcdh 
Gene Name
 Gcdh 
Gene Synonyms/Alias
 Gcdh_predicted; rCG_51052 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
60SRPVFDWKDPLVLEEacetylation[1]
172GSEEQRQKYLPRLAKacetylation[1]
211ARHNPSNKSYTLSGTacetylation[1]
249IRGFLLEKGMRGLSAacetylation[1]
262SAPRIEGKFSLRASAacetylation[1]
366CLQLGRLKDQDKATPacetylation[1]
370GRLKDQDKATPEMVSacetylation[1]
380PEMVSLLKRNNCGKAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; FAD; Flavoprotein; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 447 AA 
Protein Sequence
MVPAMLTGYM SLRGVSAWLL SRKLGLRFSR VPRTWSSAAA HTEKTQIRSV KSSRPVFDWK 60
DPLVLEEQLT ADEKLIRDTF RNYCQERLMS RILLANRNEV FHRDIVYEMG ELGVLGPTIK 120
GYGCAGVSSV AYGLLTRELE RVDSGYRSMM SVQSSLVMHP IYTYGSEEQR QKYLPRLAKG 180
ELLGCFGLTE PNHGSDPGSM ETRARHNPSN KSYTLSGTKT WITNSPVADL FVVWARCEDN 240
CIRGFLLEKG MRGLSAPRIE GKFSLRASAT GMIIMDSVEV PEENVLPNVS SLAGPFGCLN 300
TARYGITWGV LGAAEFCLHT ARQYALDRIQ FGVPLARNQL VQKKLADMLT EITLGLHACL 360
QLGRLKDQDK ATPEMVSLLK RNNCGKALDI ARQARDILGG NGISDEYHVI RHAMNLEAVN 420
TYEGTHDIHA LILGRAITGI QAFTVEK 447 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0000062; F:fatty-acyl-CoA binding; IDA:RGD.
 GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.
 GO:0004361; F:glutaryl-CoA dehydrogenase activity; IDA:RGD.
 GO:0019395; P:fatty acid oxidation; IDA:RGD.
 GO:0046949; P:fatty-acyl-CoA biosynthetic process; IDA:RGD. 
Interpro
 IPR006089; Acyl-CoA_DH_CS.
 IPR006092; Acyl-CoA_DH_N.
 IPR006090; Acyl-CoA_Oxase/DH_1.
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR009075; AcylCo_DH/oxidase_C.
 IPR013786; AcylCoA_DH/ox_N.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF00441; Acyl-CoA_dh_1
 PF02770; Acyl-CoA_dh_M
 PF02771; Acyl-CoA_dh_N 
SMART
  
PROSITE
 PS00073; ACYL_COA_DH_2 
PRINTS