UniProt Accession

 S10A4_RAT; P05942 

Genbank Protein ID

 X06916; J03628; X64022; X64023 

Genbank Nucleotide ID

 CAA30014.1; AAA42098.1 

Protein Name

 Protein S100-A4 

Protein Synonyms/Alias

 Metastasin; Nerve growth factor-induced protein 42A; P9K; Placental calcium-binding protein; S100 calcium-binding protein A4 

Gene Name

 S100a4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
26	YSGNEGDKFKLNKTE	acetylation	[1]
31	GDKFKLNKTELKELL	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 DOMAIN 12 47 EF-hand 1.
 DOMAIN 50 85 EF-hand 2.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 35 35 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Calcium; Complete proteome; Metal-binding; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 101 AA 

Protein Sequence

Gene Ontology

 GO:0043005; C:neuron projection; IDA:RGD.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0003779; F:actin binding; IDA:RGD.
 GO:0005509; F:calcium ion binding; IDA:RGD.
 GO:0048306; F:calcium-dependent protein binding; IDA:RGD.
 GO:0046982; F:protein heterodimerization activity; TAS:RGD.
 GO:0042803; F:protein homodimerization activity; TAS:RGD.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001751; S100/CaBP-9k_CS.
 IPR013787; S100_Ca-bd_sub. 

Pfam

 PF01023; S_100 

SMART

  

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00303; S100_CABP 

PRINTS