CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015722
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable peroxisomal acyl-coenzyme A oxidase 1 
Protein Synonyms/Alias
  
Gene Name
 CG5009 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
4****MPAKPVNPDLQacetylation[1]
659PVNGAFHKYLKPFMKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 MOTIF 667 669 Microbody targeting signal (Potential).
 ACT_SITE 434 434 Proton acceptor (By similarity).
 BINDING 152 152 FAD (By similarity).
 BINDING 191 191 FAD; via amide nitrogen (By similarity).
 MOD_RES 544 544 Phosphotyrosine.
 MOD_RES 551 551 Phosphoserine.  
Keyword
 Complete proteome; FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Oxidoreductase; Peroxisome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 669 AA 
Protein Sequence
MPAKPVNPDL QKERSTATFN PREFSVLWAG GEERFKEKKA LEKLFLEDPA LQDDLPISYL 60
SHKELYEHSL RKACIIGEKI RKLRADGEDG VDTYNALLGG SLGSAILKEG NPLALHYVMF 120
VPTIMGQGTM DQQVEWLSKA WDCEIIGTYA QTELGHGTFL RGLETRADYD ASTQEFVINT 180
PSLSAYKWWP GGLGHTANHA VVVAQLYTKG EFRGLAPFIV QLRDSDTHRP MPGIDIGDIG 240
TKLGMKGVNN GYLGLKNVRV PLNNMLMKNQ QVLPDGTYVA PKNSVLTYGT MMFVRCALIR 300
DTAQSLAKAS TIATRYSAVR RQSPIDPNQP EPQIMDHTTQ QLKLFPQIAK AIVFKTTGDG 360
IWNMYNVISG EIEQGNLDRL PEMHALSCCL KAICSADAAA GVETCRLSCG GHGYMDCSNF 420
PTIYGMTTAV CTYEGENTVM LLQTARYLVK VYGQALNGEK LVPTVSYISD AINQTKFVNF 480
DGSLRSIVKA FQFVAANKTR IAYEQIELRR KQGYGTEVAA NLCGTFLTAA ADLHGRAFLA 540
QTAYTELLAL SREVSPELAE VLKVVLELYL VDACLNRIGD FLRFIDLTDQ DVTKLEVRLE 600
NCLKRFRPNA VSLVDSFDLH DRVLDSALGA YDGNVYEHIF ESTKKNPLNK EPVNGAFHKY 660
LKPFMKAHL 669 
Gene Ontology
 GO:0005777; C:peroxisome; ISS:UniProtKB.
 GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0003997; F:acyl-CoA oxidase activity; ISS:UniProtKB.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IEA:UniProtKB-UniPathway.
 GO:0019395; P:fatty acid oxidation; ISS:UniProtKB.
 GO:0006091; P:generation of precursor metabolites and energy; ISS:UniProtKB.
 GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB. 
Interpro
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR012258; Acyl-CoA_oxidase.
 IPR002655; Acyl-CoA_oxidase_C.
 IPR009075; AcylCo_DH/oxidase_C.
 IPR013786; AcylCoA_DH/ox_N.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF01756; ACOX
 PF02770; Acyl-CoA_dh_M 
SMART
  
PROSITE
  
PRINTS