CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043342
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 106 
Protein Synonyms/Alias
  
Gene Name
 ZNF106 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
26NYSGPGDKFQPGRNRubiquitination[1, 2]
70WQRQENDKLGTVATYubiquitination[2, 3]
108QLESQTTKQADTATSubiquitination[4]
139WTPYPSQKTLDLQSGubiquitination[1, 2]
322NDTLRKAKEVLQCHEubiquitination[2]
340NPLLSTSKSTRNYAKubiquitination[2]
357RNVEESEKGSLKIEFmethylation[5]
433CNPIVRQKESELQMTubiquitination[2]
504PLLPELSKLGFPASLubiquitination[2, 3]
553HRKSETEKESGLKPTubiquitination[2]
558TEKESGLKPTLRQILubiquitination[2, 3]
583QVIQQVTKKKQELGKubiquitination[2]
584VIQQVTKKKQELGKGubiquitination[2]
590KKKQELGKGLPRFGIubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [5] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 816 AA 
Protein Sequence
MNNSNGNWKS SVRSTNNWNY SGPGDKFQPG RNRNSNCQME DMTMLWNKKS NKSNKYSHDR 60
YNWQRQENDK LGTVATYRGP SEGFTSDKFP SEGLLDFNFE QLESQTTKQA DTATSKVSGK 120
NGSAAREKPR RWTPYPSQKT LDLQSGLKDI TGNKSEMIEK PLFDFSLITT GIQEPQTDET 180
RNSPTQKTQK EIHTGSLNHK ASSDSAASFE VVRQCPTAEK PEQEHTPNKM PSLKSPLLPC 240
PATKSLSQKQ DPKNISKNTK TNFFSPGEHS NPSNKPTVED NHGPYISKLR SSCPHVLKGN 300
KSTFGSQKQS GDNLNDTLRK AKEVLQCHES LQNPLLSTSK STRNYAKASR NVEESEKGSL 360
KIEFQVHALE DESDGETSDT EKHGTKIGTL GSATTELLSG STRTADEKEE DDRILKTSRE 420
LSTSPCNPIV RQKESELQMT SAASPHPGLL LDLKTSLEDA QVDDSIKSHV SYETEGFESA 480
SLDAELQKSD ISQPSGPLLP ELSKLGFPAS LQRDLTRHIS LKSKTGVHLP EPNLNSARRI 540
RNISGHRKSE TEKESGLKPT LRQILNASRR NVNWEQVIQQ VTKKKQELGK GLPRFGIEMV 600
PLVQNEQEAL DLDGEPDLSS LEGFQWEGVS ISSSPGLARK RSLSESSVIM DRAPSVYSFF 660
SEEGTGKENE PQQMVSPSNS LRAGQSQKAT MHLKQEVTPR AASLRTGERA ENVATQRRHS 720
AQLSSDHIIP LMHLAKDLNS QERSIPPSEN QNSQESNGEG NCLSSSASSA LAISSLADAA 780
TDSSCTSGAE QNDGQSIRKK RRATGDGSSP ELPSLE 816 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0016020; C:membrane; IEA:Compara.
 GO:0008286; P:insulin receptor signaling pathway; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS