CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019999
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Claudin-11 
Protein Synonyms/Alias
  
Gene Name
 Cldn11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
203SSSPTHAKSAHV***ubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity). 
Sequence Annotation
 MOD_RES 197 197 Phosphoserine (By similarity).
 MOD_RES 198 198 Phosphoserine (By similarity).  
Keyword
 Cell junction; Cell membrane; Complete proteome; Direct protein sequencing; Membrane; Phosphoprotein; Reference proteome; Tight junction; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 207 AA 
Protein Sequence
MVATCLQVVG FVTSFVGWIG IIVTTSTNDW VVTCSYTIPT CRKMDELGSK GLWADCVMAT 60
GLHHCKPLVD ILILPGYAQA CRALMIAASV LGLPGILLLL TVLPCIRMGH EPGVAKYRRA 120
QLAGVLLILL ALCAIVATIW FPVCAHREIT IVSFGYSLYA GWIGAVMCLV GGCVIVCCSG 180
DAQSFGENRF YYSSGSSSPT HAKSAHV 207 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005923; C:tight junction; ISS:UniProtKB.
 GO:0042802; F:identical protein binding; ISS:UniProtKB.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB. 
Interpro
 IPR006187; Claudin.
 IPR003555; Claudin11.
 IPR017974; Claudin_CS.
 IPR004031; PMP22/EMP/MP20/Claudin. 
Pfam
 PF00822; PMP22_Claudin 
SMART
  
PROSITE
 PS01346; CLAUDIN 
PRINTS
 PR01077; CLAUDIN.
 PR01384; CLAUDIN11.