CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003537
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoside permease NupC 
Protein Synonyms/Alias
 Nucleoside-transport system protein NupC 
Gene Name
 nupC 
Gene Synonyms/Alias
 cru; b2393; JW2389 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
160AYKDILGKISRNRMYacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Transports nucleosides with a high affinity except guanosine and deoxyguanosine. Driven by a proton motive force. 
Sequence Annotation
  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 400 AA 
Protein Sequence
MDRVLHFVLA LAVVAILALL VSSDRKKIRI RYVIQLLVIE VLLAWFFLNS DVGLGFVKGF 60
SEMFEKLLGF ANEGTNFVFG SMNDQGLAFF FLKVLCPIVF ISALIGILQH IRVLPVIIRA 120
IGFLLSKVNG MGKLESFNAV SSLILGQSEN FIAYKDILGK ISRNRMYTMA ATAMSTVSMS 180
IVGAYMTMLE PKYVVAALVL NMFSTFIVLS LINPYRVDAS EENIQMSNLH EGQSFFEMLG 240
EYILAGFKVA IIVAAMLIGF IALIAALNAL FATVTGWFGY SISFQGILGY IFYPIAWVMG 300
VPSSEALQVG SIMATKLVSN EFVAMMDLQK IASTLSPRAE GIISVFLVSF ANFSSIGIIA 360
GAVKGLNEEQ GNVVSRFGLK LVYGSTLVSV LSASIAALVL 400 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:EcoCyc.
 GO:0015506; F:nucleoside:hydrogen symporter activity; IDA:EcoCyc.
 GO:0005415; F:nucleoside:sodium symporter activity; IEA:InterPro.
 GO:0015858; P:nucleoside transport; IMP:EcoCyc. 
Interpro
 IPR008276; C_nuclsd_transpt.
 IPR018270; C_nuclsd_transpt_met_bac.
 IPR011657; Nucleos_tra2_C.
 IPR002668; Nuclsd_transpt2. 
Pfam
 PF07662; Nucleos_tra2_C
 PF01773; Nucleos_tra2_N 
SMART
  
PROSITE
  
PRINTS